This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.

Input: Consider Input: TB infection begins when the mycobacteria reach the pulmonary alveoli, where they invade and replicate within endosomes of alveolar macrophages. Macrophages identify the bacterium as foreign and attempt to eliminate it by phagocytosis. During this process, the bacterium is enveloped by the macrophage and stored temporarily in a membrane-bound vesicle called a phagosome. The phagosome then combines with a lysosome to create a phagolysosome. In the phagolysosome, the cell attempts to use reactive oxygen species and acid to kill the bacterium. However, M. tuberculosis has a thick, waxy mycolic acid capsule that protects it from these toxic substances. M. tuberculosis is able to reproduce inside the macrophage and will eventually kill the immune cell.

Output: What specific part of the lungs marks the start of tuberculosis infection?


Input: Consider Input: However, Lok-Ham Chan, a professor of history at the University of Washington, writes that Changchub Gyaltsen's aims were to recreate the old Tibetan Kingdom that existed during the Chinese Tang dynasty, to build "nationalist sentiment" amongst Tibetans, and to "remove all traces of Mongol suzerainty." Georges Dreyfus, a professor of religion at Williams College, writes that it was Changchub Gyaltsen who adopted the old administrative system of Songtsän Gampo (c. 605–649)—the first leader of the Tibetan Empire to establish Tibet as a strong power—by reinstating its legal code of punishments and administrative units. For example, instead of the 13 governorships established by the Mongol Sakya viceroy, Changchub Gyaltsen divided Central Tibet into districts (dzong) with district heads (dzong dpon) who had to conform to old rituals and wear clothing styles of old Imperial Tibet. Van Praag asserts that Changchub Gyaltsen's ambitions were to "restore to Tibet the glories of its Imperial Age" by reinstating secular administration, promoting "national culture and traditions," and installing a law code that survived into the 20th century.

Output: Who divided Central Tibet into districts? 


Input: Consider Input: The first recorded European excursions into what is now called Tennessee were three expeditions led by Spanish explorers, namely Hernando de Soto in 1540, Tristan de Luna in 1559, and Juan Pardo in 1567. Pardo recorded the name "Tanasqui" from a local Indian village, which evolved to the state's current name. At that time, Tennessee was inhabited by tribes of Muscogee and Yuchi people. Possibly because of European diseases devastating the Indian tribes, which would have left a population vacuum, and also from expanding European settlement in the north, the Cherokee moved south from the area now called Virginia. As European colonists spread into the area, the Indian populations were forcibly displaced to the south and west, including all Muscogee and Yuchi peoples, the Chickasaw and Choctaw, and ultimately, the Cherokee in 1838.
Output: Which European nationality first explored the Tennessee region?