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Sentient beings always suffer throughout saṃsāra until they free themselves from this suffering (dukkha) by attaining Nirvana. Then the absence of the first Nidāna—ignorance—leads to the absence of the others.

What is the first Nidāna?
Answer: ignorance
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This article covers numbered east-west streets in Manhattan, New York City. Major streets have their own linked articles; minor streets are discussed here. The streets do not run exactly east–west, because the grid plan is aligned with the Hudson River rather than with the cardinal directions. "West" is approximately 29 degrees north of true west.

In this article, how many degrees north of true west is "West?"
Answer: 29
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St. John's was the starting point for the first non-stop transatlantic aircraft flight, by Alcock and Brown in a modified Vickers Vimy IV bomber, in June 1919, departing from Lester's Field in St. John's and ending in a bog near Clifden, Connemara, Ireland. In July 2005, the flight was duplicated by American aviator and adventurer Steve Fossett in a replica Vickers Vimy aircraft, with St. John's International Airport substituting for Lester's Field (now an urban and residential part of the city).

Who duplicated Alcock and Brown flight in 2005?
Answer:
Steve Fossett