This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.

Q: Southeast Raleigh is bounded by downtown on the west, Garner on the southwest, and rural Wake County to the southeast. The area includes areas along Rock Quarry Road, Poole Road, and New Bern Avenue. Primary neighborhoods include Chastain, Chavis Heights, Raleigh Country Club, Southgate, Kingwood Forest, Rochester Heights, Emerald Village and Biltmore Hills. Time Warner Cable Music Pavilion (formerly Alltel Pavilion and Walnut Creek Amphitheatre) is one of the region's major outdoor concert venues and is located on Rock Quarry Road. Shaw University is located in this part of the city.

A: What is to the west of Southeast Raleigh?
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Q: Regular script typefaces are also commonly used, but not as common as Ming or sans-serif typefaces for body text. Regular script typefaces are often used to teach students Chinese characters, and often aim to match the standard forms of the region where they are meant to be used. Most typefaces in the Song dynasty were regular script typefaces which resembled a particular person's handwriting (e.g. the handwriting of Ouyang Xun, Yan Zhenqing, or Liu Gongquan), while most modern regular script typefaces tend toward anonymity and regularity.

A: What are commonly used?
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Q: Firstly, flanking the open reading frame, all genes contain a regulatory sequence that is required for their expression. In order to be expressed, genes require a promoter sequence. The promoter is recognized and bound by transcription factors and RNA polymerase to initiate transcription.:7.1 A gene can have more than one promoter, resulting in messenger RNAs (mRNA) that differ in how far they extend in the 5' end. Promoter regions have a consensus sequence, however highly transcribed genes have "strong" promoter sequences that bind the transcription machinery well, whereas others have "weak" promoters that bind poorly and initiate transcription less frequently.:7.2 Eukaryotic promoter regions are much more complex and difficult to identify than prokaryotic promoters.:7.3

A:
What do all genes contain that is required for their expression?
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