Problem: The successful outcome of antimicrobial therapy with antibacterial compounds depends on several factors. These include host defense mechanisms, the location of infection, and the pharmacokinetic and pharmacodynamic properties of the antibacterial. A bactericidal activity of antibacterials may depend on the bacterial growth phase, and it often requires ongoing metabolic activity and division of bacterial cells. These findings are based on laboratory studies, and in clinical settings have also been shown to eliminate bacterial infection. Since the activity of antibacterials depends frequently on its concentration, in vitro characterization of antibacterial activity commonly includes the determination of the minimum inhibitory concentration and minimum bactericidal concentration of an antibacterial. To predict clinical outcome, the antimicrobial activity of an antibacterial is usually combined with its pharmacokinetic profile, and several pharmacological parameters are used as markers of drug efficacy.
What does the potency of antibacterials depend upon?
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Answer: concentration


Problem: The Recommended Exposure Index (REI) technique, new in the 2006 version of the standard, allows the manufacturer to specify a camera model’s EI choices arbitrarily. The choices are based solely on the manufacturer’s opinion of what EI values produce well-exposed sRGB images at the various sensor sensitivity settings. This is the only technique available under the standard for output formats that are not in the sRGB color space. This is also the only technique available under the standard when multi-zone metering (also called pattern metering) is used.
When was the Recommended Exposure Index introduced?
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Answer: 2006


Problem: In the United States and Canada, the film opened on 6 November 2015, and in its opening weekend, was originally projected to gross $70–75 million from 3,927 screens, the widest release for a Bond film. However, after grossing $5.25 million from its early Thursday night showings and $28 million on its opening day, weekend projections were increased to $75–80 million. The film ended up grossing $70.4 million in its opening weekend (about $20 million less than Skyfall's $90.6 million debut, including IMAX previews), but nevertheless finished first at the box office. IMAX generated $9.1 million for Spectre at 374 screens, premium large format made $8 million from 429 cinemas, reaping 11% of the film's opening, which means that Spectre earned $17.1 million (23%) of its opening weekend total in large-format venues. Cinemark XD generated $1.85 million in 112 XD locations.
Where was the film projected to gross $80-85 million in its opening weekend?
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Answer:
unanswerable