Problem: Pharmaceutical industry:

In many non-US western countries a 'fourth hurdle' of cost effectiveness analysis has developed before new technologies can be provided. This focuses on the efficiency (in terms of the cost per QALY) of the technologies in question rather than their efficacy. In England and Wales NICE decides whether and in what circumstances drugs and technologies will be made available by the NHS, whilst similar arrangements exist with the Scottish Medicines Consortium in Scotland, and the Pharmaceutical Benefits Advisory Committee in Australia. A product must pass the threshold for cost-effectiveness if it is to be approved. Treatments must represent 'value for money' and a net benefit to society.

Where does QALY decide whether decide in what circumstances drugs and technologies will be made available?
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A: unanswerable


Problem: Financial crisis of 2007%E2%80%9308:

CDO issuance grew from an estimated $20 billion in Q1 2004 to its peak of over $180 billion by Q1 2007, then declined back under $20 billion by Q1 2008. Further, the credit quality of CDO's declined from 2000 to 2007, as the level of subprime and other non-prime mortgage debt increased from 5% to 36% of CDO assets. As described in the section on subprime lending, the CDS and portfolio of CDS called synthetic CDO enabled a theoretically infinite amount to be wagered on the finite value of housing loans outstanding, provided that buyers and sellers of the derivatives could be found. For example, buying a CDS to insure a CDO ended up giving the seller the same risk as if they owned the CDO, when those CDO's became worthless.

What was the estimated value of CDO issuance in Q1 2004?
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A: $20 billion


Problem: MP3:

The basic MP3 decoding and encoding technology is patent-free in the European Union, all patents having expired there. In the United States, the technology will be substantially patent-free on 31 December 2017 (see below). The majority of MP3 patents expired in the US between 2007 and 2015.

Where is the basic MP3 decoding and technology patent free?
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A: European Union


Problem: Paris:

Paris hosts one of the largest science museums in Europe, the Cité des Sciences et de l'Industrie at La Villette. The National Museum of Natural History, on the Left Bank, is famous for its dinosaur artefacts, mineral collections, and its Gallery of Evolution. The military history of France, from the Middle Ages to World War II, is vividly presented by displays at the Musée de l'Armée at Les Invalides, near the tomb of Napoleon. In addition to the national museums, run by the French Ministry of Culture, the City of Paris operates 14 museums, including the Carnavalet Museum on the history of Paris; Musée d'Art Moderne de la Ville de Paris; Palais de Tokyo; the House of Victor Hugo and House of Balzac, and the Catacombs of Paris. There are also notable private museums; The Contemporary Art museum of the Louis Vuitton Foundation, designed by architect Frank Gehry, opened in October 2014 in the Bois de Boulogne.

What famous landmark is Mysee de l'Armee lat Les Invalides located ner?
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A:
the tomb of Napoleon