Hellenistic period
The Attalid dynasty of Pergamum lasted little longer; a Roman ally until the end, its final king Attalus III died in 133 BC without an heir, and taking the alliance to its natural conclusion, willed Pergamum to the Roman Republic. The final Greek resistance came in 88 BC, when King Mithridates of Pontus rebelled against Rome, captured Roman held Anatolia, and massacred up to 100,000 Romans and Roman allies across Asia Minor. Many Greek cities, including Athens, overthrew their Roman puppet rulers and joined him in the Mithridatic wars. When he was driven out of Greece by the Roman general Lucius Cornelius Sulla, who laid siege to Athens and razed the city. Mithridates was finally defeated by Gnaeus Pompeius Magnus (Pompey the Great) in 65 BC. Further ruin was brought to Greece by the Roman civil wars, which were partly fought in Greece. Finally, in 27 BC, Augustus directly annexed Greece to the new Roman Empire as the province of Achaea. The struggles with Rome had left Greece depopulated and demoralised. Nevertheless, Roman rule at least brought an end to warfare, and cities such as Athens, Corinth, Thessaloniki and Patras soon recovered their prosperity.

Q: In what year was the final Greek resistance?
88 BC