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On 25 February 1757, Burke signed a contract with Robert Dodsley to write a "history of England from the time of Julius Caesar to the end of the reign of Queen Anne", its length being eighty quarto sheets (640 pages), nearly 400,000 words. It was to be submitted for publication by Christmas 1758. Burke completed the work to the year 1216 and stopped; it was not published until after Burke's death, being included in an 1812 collection of his works, entitled An Essay Towards an Abridgement of the English History. G. M. Young did not value Burke's history and claimed that it was "demonstrably a translation from the French". Lord Acton, on commenting on the story that Burke stopped his history because David Hume published his, said "it is ever to be regretted that the reverse did not occur".

When was Burke's history of England published?
Answer: 1812
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The thalidomide tragedy resurrected Kefauver's bill to enhance drug regulation that had stalled in Congress, and the Kefauver-Harris Amendment became law on 10 October 1962. Manufacturers henceforth had to prove to FDA that their drugs were effective as well as safe before they could go on the US market. The FDA received authority to regulate advertising of prescription drugs and to establish good manufacturing practices. The law required that all drugs introduced between 1938 and 1962 had to be effective. An FDA - National Academy of Sciences collaborative study showed that nearly 40 percent of these products were not effective. A similarly comprehensive study of over-the-counter products began ten years later.

When did the Kefauver-Harris Amendment became law?
Answer: 10 October 1962
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With the decline of the Roman Empire, Alsace became the territory of the Germanic Alemanni. The Alemanni were agricultural people, and their Germanic language formed the basis of modern-day dialects spoken along the Upper Rhine (Alsatian, Alemannian, Swabian, Swiss). Clovis and the Franks defeated the Alemanni during the 5th century AD, culminating with the Battle of Tolbiac, and Alsace became part of the Kingdom of Austrasia. Under Clovis' Merovingian successors the inhabitants were Christianized. Alsace remained under Frankish control until the Frankish realm, following the Oaths of Strasbourg of 842, was formally dissolved in 843 at the Treaty of Verdun; the grandsons of Charlemagne divided the realm into three parts. Alsace formed part of the Middle Francia, which was ruled by the youngest grandson Lothar I. Lothar died early in 855 and his realm was divided into three parts. The part known as Lotharingia, or Lorraine, was given to Lothar's son. The rest was shared between Lothar's brothers Charles the Bald (ruler of the West Frankish realm) and Louis the German (ruler of the East Frankish realm). The Kingdom of Lotharingia was short-lived, however, becoming the stem duchy of Lorraine in Eastern Francia after the Treaty of Ribemont in 880. Alsace was united with the other Alemanni east of the Rhine into the stem duchy of Swabia.

Which three territories make up the Upper Rhine?
Answer:
Alsatian, Alemannian, Swabian, Swiss