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Early work in molecular genetics suggested the model that one gene makes one protein. This model has been refined since the discovery of genes that can encode multiple proteins by alternative splicing and coding sequences split in short section across the genome whose mRNAs are concatenated by trans-splicing.

What discovery caused the model that one gene makes one protein to be refined?
Answer: the discovery of genes that can encode multiple proteins
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Estonia won the Eurovision Song Contest in 2001 with the song "Everybody" performed by Tanel Padar and Dave Benton. In 2002, Estonia hosted the event. Maarja-Liis Ilus has competed for Estonia on two occasions (1996 and 1997), while Eda-Ines Etti, Koit Toome and Evelin Samuel owe their popularity partly to the Eurovision Song Contest. Lenna Kuurmaa is a very popular singer in Europe[citation needed], with her band Vanilla Ninja. "Rändajad" by Urban Symphony, was the first ever song in Estonian to chart in the UK, Belgium, and Switzerland.

What year did Estonia win the Eurovision Song Contest?
Answer: 2001
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This problem was compounded when the main Hanoverian army under Cumberland was defeated at the Battle of Hastenbeck and forced to surrender entirely at the Convention of Klosterzeven following a French Invasion of Hanover. The Convention removed Hanover and Brunswick from the war, leaving the Western approach to Prussian territory extremely vulnerable. Frederick sent urgent requests to Britain for more substantial assistance, as he was now without any outside military support for his forces in Germany.

What country won the battle at Hanover?
Answer:
French