During adolescence, the human body undergoes various physical, physiological and immunological changes triggered and mediated by hormones, of which the most significant in females is 17-β-oestradiol (an oestrogen) and, in males, is testosterone. Oestradiol usually begins to act around the age of 10 and testosterone some months later. There is evidence that these steroids act directly not only on the primary and secondary sexual characteristics but also have an effect on the development and regulation of the immune system, including an increased risk in developing pubescent and post-pubescent autoimmunity. There is also some evidence that cell surface receptors on B cells and macrophages may detect sex hormones in the system.
Which specific hormone precipitates the change in immunology in males?
testosterone


Input: Gramophone record
New or "virgin" heavy/heavyweight (180–220 g) vinyl is commonly used for modern audiophile vinyl releases in all genres. Many collectors prefer to have heavyweight vinyl albums, which have been reported to have better sound than normal vinyl because of their higher tolerance against deformation caused by normal play. 180 g vinyl is more expensive to produce only because it uses more vinyl. Manufacturing processes are identical regardless of weight. In fact, pressing lightweight records requires more care. An exception is the propensity of 200 g pressings to be slightly more prone to non-fill, when the vinyl biscuit does not sufficiently fill a deep groove during pressing (percussion or vocal amplitude changes are the usual locations of these artifacts). This flaw causes a grinding or scratching sound at the non-fill point.

Would would a non filled area in a vinyl press cause when listening to a record?
Output: grinding or scratching sound


Input: Article: Three milestone releases of Windows 8 leaked to the general public. Milestone 1, Build 7850, was leaked on April 12, 2011. It was the first build where the text of a window was written centered instead of aligned to the left. It was also probably the first appearance of the Metro-style font, and its wallpaper had the text shhh... let's not leak our hard work. However, its detailed build number reveals that the build was created on September 22, 2010. The leaked copy edition was Enterprise edition. The OS still reads as "Windows 7". Milestone 2, Build 7955, was leaked on April 25, 2011. The traditional Blue Screen of Death (BSoD) was replaced by a new Black screen, although this was later scrapped. This build introduced a new ribbon in Windows Explorer. Build 7959, with minor changes but the first 64-bit version, was leaked on May 1, 2011. The "Windows 7" logo was temporarily replaced with text displaying "Microsoft Confidential". On June 17, 2011, build 7989 64-bit edition was leaked. It introduced a new boot screen featuring the same fish as the default Windows 7 Beta wallpaper, which was later scrapped, and the circling dots as featured in the final (although the final version comes with smaller circling dots throbber). It also had the text Welcome below them, although this was also scrapped.

Now answer this question: When was Milestone 1 divulged?

Output: April 12, 2011


Article: On the Origin of Species was first published on Thursday 24 November 1859, priced at fifteen shillings with a first printing of 1250 copies. The book had been offered to booksellers at Murray's autumn sale on Tuesday 22 November, and all available copies had been taken up immediately. In total, 1,250 copies were printed but after deducting presentation and review copies, and five for Stationers' Hall copyright, around 1,170 copies were available for sale. Significantly, 500 were taken by Mudie's Library, ensuring that the book promptly reached a large number of subscribers to the library. The second edition of 3,000 copies was quickly brought out on 7 January 1860, and incorporated numerous corrections as well as a response to religious objections by the addition of a new epigraph on page ii, a quotation from Charles Kingsley, and the phrase "by the Creator" added to the closing sentence. During Darwin's lifetime the book went through six editions, with cumulative changes and revisions to deal with counter-arguments raised. The third edition came out in 1861, with a number of sentences rewritten or added and an introductory appendix, An Historical Sketch of the Recent Progress of Opinion on the Origin of Species, while the fourth in 1866 had further revisions. The fifth edition, published on 10 February 1869, incorporated more changes and for the first time included the phrase "survival of the fittest", which had been coined by the philosopher Herbert Spencer in his Principles of Biology (1864).

Question: What was the cost for the first published copies of On the Origin of Species?
Ans: fifteen shillings


Here is a question about this article: Hunter-gatherer societies manifest significant variability, depending on climate zone/life zone, available technology and societal structure. Archaeologists examine hunter-gatherer tool kits to measure variability across different groups. Collard et al. (2005) found temperature to be the only statistically significant factor to impact hunter-gatherer tool kits. Using temperature as a proxy for risk, Collard et al.'s results suggest that environments with extreme temperatures pose a threat to hunter-gatherer systems significant enough to warrant increased variability of tools. These results support Torrence's (1989) theory that risk of failure is indeed the most important factor in determining the structure of hunter-gatherer toolkits.
What is the answer to this question: What does temperature impact on tool kits?
****
So... increased variability of tools


Article: When a USB device is first connected to a USB host, the USB device enumeration process is started. The enumeration starts by sending a reset signal to the USB device. The data rate of the USB device is determined during the reset signaling. After reset, the USB device's information is read by the host and the device is assigned a unique 7-bit address. If the device is supported by the host, the device drivers needed for communicating with the device are loaded and the device is set to a configured state. If the USB host is restarted, the enumeration process is repeated for all connected devices.

Question: What id the data rate determined during?
Ans:
the reset signaling