After losing an extra-inning game in Game 1, the Cubs rallied and took a 3 games to 1 lead over the Wild Card Florida Marlins in the NLCS. Florida shut the Cubs out in Game 5, but young pitcher Mark Prior led the Cubs in Game 6 as they took a 3–0 lead into the 8th inning and it was at this point when a now-infamous incident took place. Several spectators attempted to catch a foul ball off the bat of Luis Castillo. A Chicago Cubs fan by the name of Steve Bartman, of Northbrook, Illinois, reached for the ball and deflected it away from the glove of Moisés Alou for the second out of the 8th inning. Alou reacted angrily toward the stands, and after the game stated that he would have caught the ball. Alou at one point recanted, saying he would not have been able to make the play, but later said this was just an attempt to make Bartman feel better and believing the whole incident should be forgotten. Interference was not called on the play, as the ball was ruled to be on the spectator side of the wall. Castillo was eventually walked by Prior. Two batters later, and to the chagrin of the packed stadium, Cubs shortstop Alex Gonzalez misplayed an inning ending double play, loading the bases and leading to eight Florida runs and a Marlin victory. Despite sending Kerry Wood to the mound and holding a lead twice, the Cubs ultimately dropped Game 7, and failed to reach the World Series.

In what game did Florida shut the Cubs out?