Problem: Pharmaceutical industry:

By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extracts were of particular interest to surgeons as hemostatic agents and as treatment for shock, and a number of companies developed products based on adrenal extracts containing varying purities of the active substance. In 1897 John Abel of Johns Hopkins University identified the active principle as epinephrine, which he isolated in an impure state as the sulfate salt. Industrial chemist Jokichi Takamine later developed a method for obtaining epinephrine in a pure state, and licensed the technology to Parke Davis. Parke Davis marketed epinephrine under the trade name Adrenalin. Injected epinephrine proved to be especially efficacious for the acute treatment of asthma attacks, and an inhaled version was sold in the United States until 2011 (Primatene Mist). By 1929 epinephrine had been formulated into an inhaler for use in the treatment of nasal congestion.

Who first discovered epinephrine?
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A: John Abel


Problem: The Bronx:

At the 2009 American Community Survey, Black Americans made the second largest group in the Bronx after Hispanics and Latinos. Blacks of both Hispanic and non-Hispanic origin represented over one-third (35.4%) of the Bronx's population. Blacks of non-Hispanic origin made up 30.8% of the population. Over 495,200 blacks resided in the borough, of which 430,600 were non-Hispanic blacks. Over 61,000 people identified themselves as "Sub-Saharan African" in the survey, making up 4.4% of the population.

How many Bronx residents called themselves "Sub-Saharan African" in 2009?
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A: Over 61,000


Problem: British Empire:

The Napoleonic Wars were therefore ones in which Britain invested large amounts of capital and resources to win. French ports were blockaded by the Royal Navy, which won a decisive victory over a Franco-Spanish fleet at Trafalgar in 1805. Overseas colonies were attacked and occupied, including those of the Netherlands, which was annexed by Napoleon in 1810. France was finally defeated by a coalition of European armies in 1815. Britain was again the beneficiary of peace treaties: France ceded the Ionian Islands, Malta (which it had occupied in 1797 and 1798 respectively), Mauritius, St Lucia, and Tobago; Spain ceded Trinidad; the Netherlands Guyana, and the Cape Colony. Britain returned Guadeloupe, Martinique, French Guiana, and Réunion to France, and Java and Suriname to the Netherlands, while gaining control of Ceylon (1795–1815).

When was Napoleon finally defeated?
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A: 1815


Problem: Thuringia:

The landscapes of Thuringia are quite diverse. The far north is occupied by the Harz mountains, followed by the Goldene Aue, a fertile floodplain around Nordhausen with the Helme as most important river. The north-west includes the Eichsfeld, a hilly and sometimes forested region, where the Leine river emanates. The central and northern part of Thuringia is defined by the 3000 km² wide Thuringian Basin, a very fertile and flat area around the Unstrut river and completely surrounded by the following hill chains (clockwise from the north-west): Dün, Hainleite, Windleite, Kyffhäuser, Hohe Schrecke, Schmücke, Finne, Ettersberg, Steigerwald, Thuringian Forest, Hörselberge and Hainich. Within the Basin the smaller hill chains Fahner Höhe and Heilinger Höhen. South of the Thuringian Basin is the Land's largest mountain range, marked by the Thuringian Forest in the north-west, the Thuringian Highland in the middle and the Franconian Forest in the south-east. Most of this range is forested and the Großer Beerberg (983 m) is Thuringia's highest mountain. To the south-west, the Forest is followed up by Werra river valley, dividing it from the Rhön Mountains in the west and the Grabfeld plain in the south. Eastern Thuringia, commonly described as the area east of Saale and Loquitz valley, is marked by a hilly landscape, rising slowly from the flat north to the mountainous south. The Saale in the west and the Weiße Elster in the east are the two big rivers running from south to north and forming densely settled valleys in this area. Between them lies the flat and forested Holzland in the north, the flat and fertile Orlasenke in the middle and the Vogtland, a hilly but in most parts non-forested region in the south. The far eastern region (east of Weiße Elster) is the Osterland or Altenburger Land along Pleiße river, a flat, fertile and densely settled agricultural area.

How many big rivers flow through Thuringia? 
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A:
The Saale in the west and the Weiße Elster in the east