Institute of Medicine, the central college of Tribhuwan University is the first medical college of Nepal and is located in Maharajgunj, Kathmandu. It was established in 1972 and started to impart medical education from 1978. A number of medical colleges including Kathmandu Medical College, Nepal Medical College, KIST Medical College, Nepal Army Institute of Health Sciences, National Academy of Medical Sciences (NAMS) and Kathmandu University School of Medical Sciences (KUSMS), are also located in or around Kathmandu.

Of what university is the Institute of Medicine a constituent college?