Question: Breakthrough pain is transitory acute pain that comes on suddenly and is not alleviated by the patient's normal pain management. It is common in cancer patients who often have background pain that is generally well-controlled by medications, but who also sometimes experience bouts of severe pain that from time to time "breaks through" the medication. The characteristics of breakthrough cancer pain vary from person to person and according to the cause. Management of breakthrough pain can entail intensive use of opioids, including fentanyl.
Is there an answer to this question: What does management of acute transitory pain entail?

Answer: unanswerable


Question: Old English is one of the West Germanic languages, and its closest relatives are Old Frisian and Old Saxon. Like other old Germanic languages, it is very different from Modern English and difficult for Modern English speakers to understand without study. Old English grammar is quite similar to that of modern German: nouns, adjectives, pronouns, and verbs have many inflectional endings and forms, and word order is much freer. The oldest Old English inscriptions were written using a runic system, but from about the 9th century this was replaced by a version of the Latin alphabet.
Is there an answer to this question: In what century did the Latin alphabet replace the runic system in Old English writing?

Answer: 9th


Question: The original model Famicom featured two game controllers, both of which were hardwired to the back of the console. The second controller lacked the START and SELECT buttons, but featured a small microphone. Relatively few games made use of this feature. The earliest produced Famicom units initially had square A and B buttons. This was changed to the circular designs because of the square buttons being caught in the controller casing when pressed down and glitches within the hardware causing the system to freeze occasionally while playing a game.
Is there an answer to this question: What shape did the A and B buttons eventually become?

Answer: circular


Question: All vertebrate brains share a common underlying form, which appears most clearly during early stages of embryonic development. In its earliest form, the brain appears as three swellings at the front end of the neural tube; these swellings eventually become the forebrain, midbrain, and hindbrain (the prosencephalon, mesencephalon, and rhombencephalon, respectively). At the earliest stages of brain development, the three areas are roughly equal in size. In many classes of vertebrates, such as fish and amphibians, the three parts remain similar in size in the adult, but in mammals the forebrain becomes much larger than the other parts, and the midbrain becomes very small.
Is there an answer to this question: The forebrain during development is known as what?

Answer:
prosencephalon