Input: Read this: Obesity can unfavourably alter hormonal and metabolic status via resistance to the hormone leptin, and a vicious cycle may occur in which insulin/leptin resistance and obesity aggravate one another. The vicious cycle is putatively fuelled by continuously high insulin/leptin stimulation and fat storage, as a result of high intake of strongly insulin/leptin stimulating foods and energy. Both insulin and leptin normally function as satiety signals to the hypothalamus in the brain; however, insulin/leptin resistance may reduce this signal and therefore allow continued overfeeding despite large body fat stores. In addition, reduced leptin signalling to the brain may reduce leptin's normal effect to maintain an appropriately high metabolic rate.
Question: In the so called vicious cycle, what aggravates obesity to continue the cycle?

Output: insulin/leptin resistance


QUES: The undergraduates have a number of traditions: Painting The Rock (originally a fountain donated by the Class of 1902) is a way to advertise, for example, campus organizations, events in Greek life, student groups, and university-wide events. Dance Marathon, a 30-hour philanthropic event, has raised more than 13 million dollars in its history for various children's charities. Primal Scream is held at 9 p.m. on the Sunday before finals week every quarter; students lean out of windows or gather in courtyards and scream. Armadillo Day, or, more popularly, Dillo Day, a day of music and food, is held on Northwestern's Lakefill every Spring on the weekend after Memorial Day. And in one of the University's newer traditions, every year during freshman orientation, known as Wildcat Welcome, freshmen and transfer students pass through Weber Arch to the loud huzzahs of upperclassmen and the music of the University Marching Band.

How much money has the traditional Southwestern Dance Marathon raised for children's charities?
What is the answer?
ANS: unanswerable


QUES: The Farmington Canal Trail is a rail trail that will eventually run continuously from downtown New Haven to Northampton, Massachusetts. The scenic trail follows the path of the historic New Haven and Northampton Company and the Farmington Canal. Currently, there is a continuous 14-mile (23 km) stretch of the trail from downtown, through Hamden and into Cheshire, making bicycle commuting between New Haven and those suburbs possible. The trail is part of the East Coast Greenway, a proposed 3,000-mile (4,800 km) bike path that would link every major city on the East Coast from Florida to Maine.
In terms of length, how long is the East Coast Greenway trail if it stretches from Maine to Florida?

ANS: 3,000-mile


At the Abbey Saint-Denis, Noyon Cathedral, Notre Dame de Paris and at the eastern end of Canterbury Cathedral in England, simple cylindrical columns predominate over the Gothic forms of clustered columns and shafted piers. Wells Cathedral in England, commenced at the eastern end in 1175, was the first building in which the designer broke free from Romanesque forms. The architect entirely dispensed with the round arch in favour of the pointed arch and with cylindrical columns in favour of piers composed of clusters of shafts which lead into the mouldings of the arches. The transepts and nave were continued by Adam Locke in the same style and completed in about 1230. The character of the building is entirely Gothic. Wells Cathedral is thus considered the first truly Gothic cathedral.
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): When was the construction of Wells Cathedral in England begun?
Ah, so.. in 1175


Question: On 14 October, the heaviest night attack to date saw 380 German bombers from Luftflotte 3 hit London. Around 200 people were killed and another 2,000 injured. British anti-aircraft defences (General Frederick Alfred Pile) fired 8,326 rounds and shot down only two bombers. On 15 October, the bombers returned and about 900 fires were started by the mix of 415 short tons (376 t) of high explosive and 11 short tons (10.0 t) of incendiaries dropped. Five main rail lines were cut in London and rolling stock damaged.
Try to answer this question if possible: How many German bombers were shot down?
Answer: two


Problem: There were 112,608 households in the city in 2000, of which 26.5% included children below the age of 18, 39.5% were composed of married couples living together, 11.4% reported a female householder with no husband present, and 45.5% classified themselves as nonfamily. Unmarried partners were present in 2.2% of households. In addition, 33.1% of all households were composed of individuals living alone, of which 6.2% was someone 65 years of age or older. The average household size in Raleigh was 2.30 persons, and the average family size was 2.97 persons.
What percentage were 70 and older?
---
Answer:
unanswerable