Please answer a question about the following article about Empiricism:

In the late renaissance various writers began to question the medieval and classical understanding of knowledge acquisition in a more fundamental way. In political and historical writing Niccolò Machiavelli and his friend Francesco Guicciardini initiated a new realistic style of writing. Machiavelli in particular was scornful of writers on politics who judged everything in comparison to mental ideals and demanded that people should study the "effectual truth" instead. Their contemporary, Leonardo da Vinci (1452–1519) said, "If you find from your own experience that something is a fact and it contradicts what some authority has written down, then you must abandon the authority and base your reasoning on your own findings."

When did da Vinci die?
1519