QUES: In 1903 Hermann Emil Fischer and Joseph von Mering disclosed their discovery that diethylbarbituric acid, formed from the reaction of diethylmalonic acid, phosphorus oxychloride and urea, induces sleep in dogs. The discovery was patented and licensed to Bayer pharmaceuticals, which marketed the compound under the trade name Veronal as a sleep aid beginning in 1904. Systematic investigations of the effect of structural changes on potency and duration of action led to the discovery of phenobarbital at Bayer in 1911 and the discovery of its potent anti-epileptic activity in 1912. Phenobarbital was among the most widely used drugs for the treatment of epilepsy through the 1970s, and as of 2014, remains on the World Health Organizations list of essential medications. The 1950s and 1960s saw increased awareness of the addictive properties and abuse potential of barbiturates and amphetamines and led to increasing restrictions on their use and growing government oversight of prescribers. Today, amphetamine is largely restricted to use in the treatment of attention deficit disorder and phenobarbital in the treatment of epilepsy.
Who discovered a reaction that induced sleep in dogs?

ANS: Hermann Emil Fischer and Joseph von Mering

QUES: In 2013 it was found that the Ministry of Defence had overspent on its equipment budget by £6.5bn on orders that could take up to 39 years to fulfil. The Ministry of Defence has been criticised in the past for poor management and financial control, investing in projects that have taken up to 10 and even as much as 15 years to be delivered.
Past projects ordered by the MoD have taken what type of time frame to fulfill?

ANS: up to 10 and even as much as 15 years

QUES: Many more of the control codes have been given meanings quite different from their original ones. The "escape" character (ESC, code 27), for example, was intended originally to allow sending other control characters as literals instead of invoking their meaning. This is the same meaning of "escape" encountered in URL encodings, C language strings, and other systems where certain characters have a reserved meaning. Over time this meaning has been co-opted and has eventually been changed. In modern use, an ESC sent to the terminal usually indicates the start of a command sequence, usually in the form of a so-called "ANSI escape code" (or, more properly, a "Control Sequence Introducer") beginning with ESC followed by a "[" (left-bracket) character. An ESC sent from the terminal is most often used as an out-of-band character used to terminate an operation, as in the TECO and vi text editors. In graphical user interface (GUI) and windowing systems, ESC generally causes an application to abort its current operation or to exit (terminate) altogether.
What was the "escape" character originally intended for?

ANS: to allow sending other control characters as literals instead of invoking their meaning

QUES: The Early Cretaceous spans from 145 million to 100 million years ago. The Early Cretaceous saw the expansion of seaways, and as a result, the decline and extinction of sauropods (except in South America). Many coastal shallows were created, and that caused Ichthyosaurs to die out. Mosasaurs evolved to replace them as head of the seas. Some island-hopping dinosaurs, like Eustreptospondylus, evolved to cope with the coastal shallows and small islands of ancient Europe. Other dinosaurs rose up to fill the empty space that the Jurassic-Cretaceous extinction left behind, such as Carcharodontosaurus and Spinosaurus. Of the most successful would be the Iguanodon which spread to every continent. Seasons came back into effect and the poles got seasonally colder, but dinosaurs still inhabited this area like the Leaellynasaura which inhabited the polar forests year-round, and many dinosaurs migrated there during summer like Muttaburrasaurus. Since it was too cold for crocodiles, it was the last stronghold for large amphibians, like Koolasuchus. Pterosaurs got larger as species like Tapejara and Ornithocheirus evolved.
What dinosaur spread to every continent?

ANS:
Iguanodon