The earliest evidence of cotton use in South Asia has been found at the site of Mehrgarh, Pakistan, where cotton threads have been found preserved in copper beads; these finds have been dated to Neolithic (between 6000 and 5000 BCE). Cotton cultivation in the region is dated to the Indus Valley Civilization, which covered parts of modern eastern Pakistan and northwestern India between 3300 and 1300 BCE The Indus cotton industry was well-developed and some methods used in cotton spinning and fabrication continued to be used until the industrialization of India. Between 2000 and 1000 BC cotton became widespread across much of India. For example, it has been found at the site of Hallus in Karnataka dating from around 1000 BC.

Where in Southeast Asia has early use of cotton been discovered?