Additionally, genes can have regulatory regions many kilobases upstream or downstream of the open reading frame. These act by binding to transcription factors which then cause the DNA to loop so that the regulatory sequence (and bound transcription factor) become close to the RNA polymerase binding site. For example, enhancers increase transcription by binding an activator protein which then helps to recruit the RNA polymerase to the promoter; conversely silencers bind repressor proteins and make the DNA less available for RNA polymerase.
What happens after an enhancer binds an activator protein?
helps to recruit the RNA polymerase to the promoter


Input: Szlachta
In the 1840s Nicholas I reduced 64,000 szlachta to commoner status. Despite this, 62.8% of Russia's nobles were szlachta in 1858 and still 46.1% in 1897. Serfdom was abolished in Russian Poland on February 19, 1864. It was deliberately enacted in a way that would ruin the szlachta. It was the only area where peasants paid the market price in redemption for the land (the average for the empire was 34% above the market price). All land taken from Polish peasants since 1846 was to be returned without redemption payments. The ex serfs could only sell land to other peasants, not szlachta. 90% of the ex serfs in the empire who actually gained land after 1861 were in the 8 western provinces. Along with Romania, Polish landless or domestic serfs were the only ones to be given land after serfdom was abolished. All this was to punish the szlachta's role in the uprisings of 1830 and 1863. By 1864 80% of szlachta were déclassé, 1/4 petty nobles were worse off than the average serf, 48.9% of land in Russian Poland was in peasant hands, nobles still held 46%. In Second Polish Republic the privileges of the nobility were lawfully abolished by the March Constitution in 1921 and as such not granted by any future Polish law.

How much land was held by the peasants? 
Output: 48.9%


Input: Article: The expansive area northwest of the city limits is diverse, ranging from the rural communities of Catalina and parts of the town of Marana, the small suburb of Picture Rocks, the affluent town of Oro Valley in the western foothills of the Santa Catalina Mountains, and residential areas in the northeastern foothills of the Tucson Mountains. Continental Ranch (Marana), Dove Mountain (Marana), and Rancho Vistoso (Oro Valley) are all masterplanned communities located in the Northwest, where thousands of residents live.

Now answer this question: Which town would you find Dove Mountain and Continental Ranch?

Output: Marana


Article: Stansted Airport, north east of London in Essex, is a local UK hub and Luton Airport to the north of London in Bedfordshire, caters mostly for cheap short-haul flights. London City Airport, the smallest and most central airport, in Newham, East London, is focused on business travellers, with a mixture of full service short-haul scheduled flights and considerable business jet traffic. London Southend Airport, east of London in Essex, is a smaller, regional airport that mainly caters for cheap short-haul flights.

Question: London City Airport's clients are comprised chiefly of what?
Ans: business travellers


Here is a question about this article: Pesticides may cause acute and delayed health effects in people who are exposed. Pesticide exposure can cause a variety of adverse health effects, ranging from simple irritation of the skin and eyes to more severe effects such as affecting the nervous system, mimicking hormones causing reproductive problems, and also causing cancer. A 2007 systematic review found that "most studies on non-Hodgkin lymphoma and leukemia showed positive associations with pesticide exposure" and thus concluded that cosmetic use of pesticides should be decreased. There is substantial evidence of associations between organophosphate insecticide exposures and neurobehavioral alterations.  Limited evidence also exists for other negative outcomes from pesticide exposure including neurological, birth defects, fetal death,
What is the answer to this question: What is one of the most serious effects of exposure to pesticides?
****
So... cancer


Article: In the past, the floor exercise event was executed on the bare floor or mats such as wrestling mats. Today, the floor event occurs on a carpeted 12m × 12m square, usually consisting of hard foam over a layer of plywood, which is supported by springs or foam blocks generally called a "spring" floor. This provides a firm surface that provides extra bounce or spring when compressed, allowing gymnasts to achieve greater height and a softer landing after the composed skill. Gymnasts perform a choreographed routine up to 90 seconds in the floor exercise event; Depending on the level, they may choose their own, or, if known as a "compulsory gymnast," default music must be played. In some gymnastic associations such as United States Association of Gymnastic Clubs (USAIGC), gymnasts are allowed to have vocals in their music but at USA Gymnastics competitions a large deduction is taken from the score for having vocals in the music. The routine should consist of tumbling lines, series of jumps, leaps, dance elements, acrobatic skills, and turns, or piviots, on one foot. A gymnast can perform up to four tumbling lines that usually includes at least one flight element without hand support. Each level of gymnastics requires the athlete to perform a different number of tumbling passes. In level 7 in the United States, a gymnast is required to do 2–3, and in levels 8–10, at least 3–4 tumbling passes are required.

Question: Why helps add an extra bounce to the floor?
Ans:
springs or foam blocks generally called a "spring" floor