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There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act.  Because medical research and development of drugs to treat such diseases is financially disadvantageous, companies that do so are rewarded with tax reductions, fee waivers, and market exclusivity on that drug for a limited time (seven years), regardless of whether the drug is protected by patents.

What is one financial benefit to researching orphan drugs?
Answer: tax reductions
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Inns are buildings where travellers can seek lodging and, usually, food and drink. They are typically located in the country or along a highway. In Europe, they possibly first sprang up when the Romans built a system of roads two millennia ago.[citation needed] Some inns in Europe are several centuries old. In addition to providing for the needs of travellers, inns traditionally acted as community gathering places.

How many thousand years ago did the Romans build their road system?
Answer: two
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Financial problems and a reduction in tourism led to Norfolk Island's administration appealing to the Australian federal government for assistance in 2010. In return, the islanders were to pay income tax for the first time but would be eligible for greater welfare benefits. However, by May 2013 agreement had not been reached and islanders were having to leave to find work and welfare. An agreement was finally signed in Canberra on 12 March 2015 to replace self-government with a local council but against the wishes of the Norfolk Island government. A majority of Norfolk Islanders have objected to the Australian plan to make changes to Norfolk Island without first consulting them and allowing their say with 68% of voters against forced changes.

An agreement was finally signed in Canberra on March 12, 2015, to do what for Norfolk Island?
Answer:
replace self-government with a local council