In the general election, against the advice of his advisors, Eisenhower insisted on campaigning in the South, refusing to surrender the region to the Democratic Party. The campaign strategy, dubbed "K1C2", was to focus on attacking the Truman and Roosevelt administrations on three issues: Korea, Communism and corruption. In an effort to accommodate the right, he stressed that the liberation of Eastern Europe should be by peaceful means only; he also distanced himself from his former boss President Truman.

In what part of the country, previously neglected by Republican presidential candidates, did Eisenhower campaign?