Problem: The BCG vaccine has limitations, and research to develop new TB vaccines is ongoing. A number of potential candidates are currently in phase I and II clinical trials. Two main approaches are being used to attempt to improve the efficacy of available vaccines. One approach involves adding a subunit vaccine to BCG, while the other strategy is attempting to create new and better live vaccines. MVA85A, an example of a subunit vaccine, currently in trials in South Africa, is based on a genetically modified vaccinia virus. Vaccines are hoped to play a significant role in treatment of both latent and active disease.
What genetically modified virus was used to develop MVA85A?
The answer is the following: vaccinia


Precipitation is moderate and somewhat evenly distributed throughout the year, although the warmer months such as May and June average more, averaging 33.5 inches (850 mm) annually, but historically ranging from 20.49 in (520 mm) in 1963 to 47.70 in (1,212 mm) in 2011. Snowfall, which typically falls in measurable amounts between November 15 through April 4 (occasionally in October and very rarely in May), averages 42.5 inches (108 cm) per season, although historically ranging from 11.5 in (29 cm) in 1881−82 to 94.9 in (241 cm) in 2013−14. A thick snowpack is not often seen, with an average of only 27.5 days with 3 in (7.6 cm) or more of snow cover. Thunderstorms are frequent in the Detroit area. These usually occur during spring and summer.
What is the average rainfall for summer months?
33.5 inches


Input: Philadelphia
Before Europeans arrived, the Philadelphia area was home to the Lenape (Delaware) Indians in the village of Shackamaxon. The Lenape are a Native American tribe and First Nations band government. They are also called Delaware Indians and their historical territory was along the Delaware River watershed, western Long Island and the Lower Hudson Valley.[a] Most Lenape were pushed out of their Delaware homeland during the 18th century by expanding European colonies, exacerbated by losses from intertribal conflicts. Lenape communities were weakened by newly introduced diseases, mainly smallpox, and violent conflict with Europeans. Iroquois people occasionally fought the Lenape. Surviving Lenape moved west into the upper Ohio River basin. The American Revolutionary War and United States' independence pushed them further west. In the 1860s, the United States government sent most Lenape remaining in the eastern United States to the Indian Territory (present-day Oklahoma and surrounding territory) under the Indian removal policy. In the 21st century, most Lenape now reside in the US state of Oklahoma, with some communities living also in Wisconsin, Ontario (Canada) and in their traditional homelands.

What disease killed the most Lenape?
Output: smallpox


Input: Article: The Hephthalites (or Ephthalites), also known as the White Huns, were a nomadic confederation in Central Asia during the late antiquity period. The White Huns established themselves in modern-day Afghanistan by the first half of the 5th century. Led by the Hun military leader Toramana, they overran the northern region of Pakistan and North India. Toramana's son Mihirakula, a Saivite Hindu, moved up to near Pataliputra to the east and Gwalior to the central India. Hiuen Tsiang narrates Mihirakula's merciless persecution of Buddhists and destruction of monasteries, though the description is disputed as far as the authenticity is concerned. The Huns were defeated by the Indian kings Yasodharman of Malwa and Narasimhagupta in the 6th century. Some of them were driven out of India and others were assimilated in the Indian society.

Now answer this question: What type of trib were the Hephthalites?

Output: nomadic confederation


Article: Enlightenment historiography began in the period itself, from what Enlightenment figures said about their work. A dominant element was the intellectual angle they took. D'Alembert's Preliminary Discourse of l'Encyclopédie provides a history of the Enlightenment which comprises a chronological list of developments in the realm of knowledge – of which the Encyclopédie forms the pinnacle. In 1783, Jewish philosopher Moses Mendelssohn referred to Enlightenment as a process by which man was educated in the use of reason. Immanuel Kant called Enlightenment "man's release from his self-incurred tutelage", tutelage being "man's inability to make use of his understanding without direction from another". "For Kant, Enlightenment was mankind's final coming of age, the emancipation of the human consciousness from an immature state of ignorance." The German scholar Ernst Cassirer called the Enlightenment "a part and a special phase of that whole intellectual development through which modern philosophic thought gained its characteristic self-confidence and self-consciousness". According to historian Roy Porter, the liberation of the human mind from a dogmatic state of ignorance is the epitome of what the Age of Enlightenment was trying to capture.

Question: For whom was Enlightenment mankind's final coming of age, the emancipation of the human consciousness from an immature state of ignorance?"
Ans: Immanuel Kant


Input: Namibia
Namibia is the driest country in sub-Saharan Africa and depends largely on groundwater. With an average rainfall of about 350 mm per annum, the highest rainfall occurs in the Caprivi in the northeast (about 600 mm per annum) and decreases in a westerly and southwesterly direction to as little as 50 mm and less per annum at the coast. The only perennial rivers are found on the national borders with South Africa, Angola, Zambia, and the short border with Botswana in the Caprivi. In the interior of the country surface water is available only in the summer months when rivers are in flood after exceptional rainfalls. Otherwise, surface water is restricted to a few large storage dams retaining and damming up these seasonal floods and their runoff. Thus, where people don’t live near perennial rivers or make use of the storage dams, they are dependent on groundwater. The advantage of using groundwater sources is that even isolated communities and those economic activities located far from good surface water sources such as mining, agriculture, and tourism can be supplied from groundwater over nearly 80% of the country.

What is the average rainfall in Namibia?
Output:
350 mm per annum