The West Campus is located about one mile (1.6 km) to the west of the Danforth Campus in Clayton, Missouri, and primarily consists of a four-story former department store building housing mostly administrative space. The West Campus building was home to the Clayton branch of the Famous-Barr department store until 1990, when the University acquired the property and adjacent parking and began a series of renovations. Today, the basement level houses the West Campus Library, the University Archives, the Modern Graphic History Library, and conference space. The ground level still remains a retail space. The upper floors house consolidated capital gifts, portions of alumni and development, and information systems offices from across the Danforth and Medical School campuses. There is also a music rehearsal room on the second floor. The West Campus is also home to the Center for the Application of Information Technologies (CAIT), which provides IT training services.

Where is the West Campus of Washington University located?