Problem: A much smaller number of people are insensitive to pain due to an inborn abnormality of the nervous system, known as "congenital insensitivity to pain". Children with this condition incur carelessly-repeated damage to their tongues, eyes, joints, skin, and muscles. Some die before adulthood, and others have a reduced life expectancy.[citation needed] Most people with congenital insensitivity to pain have one of five hereditary sensory and autonomic neuropathies (which includes familial dysautonomia and congenital insensitivity to pain with anhidrosis). These conditions feature decreased sensitivity to pain together with other neurological abnormalities, particularly of the autonomic nervous system. A very rare syndrome with isolated congenital insensitivity to pain has been linked with mutations in the SCN9A gene, which codes for a sodium channel (Nav1.7) necessary in conducting pain nerve stimuli.
What is an insensitivity to congenital pain?
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Answer: unanswerable


Problem: A microbrewery, or craft brewery, produces a limited amount of beer. The maximum amount of beer a brewery can produce and still be classed as a microbrewery varies by region and by authority, though is usually around 15,000 barrels (1.8 megalitres, 396 thousand imperial gallons or 475 thousand US gallons) a year. A brewpub is a type of microbrewery that incorporates a pub or other eating establishment. The highest density of breweries in the world, most of them microbreweries, exists in the German Region of Franconia, especially in the district of Upper Franconia, which has about 200 breweries. The Benedictine Weihenstephan Brewery in Bavaria, Germany, can trace its roots to the year 768, as a document from that year refers to a hop garden in the area paying a tithe to the monastery. The brewery was licensed by the City of Freising in 1040, and therefore is the oldest working brewery in the world.
What is a brewery called that makes a small amount of beer?
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Answer: microbrewery


Problem: The major settlements in the ceremonial county are concentrated on the Fylde coast (the Blackpool Urban Area), and a belt of towns running west-east along the M65: Preston, Blackburn, Accrington, Burnley, Nelson and Colne. South of Preston are the towns of Leyland and Chorley; the three formed part of the Central Lancashire New Town designated in 1970. The north of the county is predominantly rural and sparsely populated, except for the towns of Lancaster and Morecambe which form a large conurbation of almost 100,000 people. Lancashire is home to a significant Asian population, numbering over 70,000 and 6% of the county's population, and concentrated largely in the former cotton mill towns in the south east.
In what year was the Blackpool Urban Area established?
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Answer:
unanswerable