The franchise was first created in 1997 as a series of virtual pets, akin to—and influenced in style by—the contemporary Tamagotchi or nano Giga Pet toys. The creatures were first designed to look cute and iconic even on the devices' small screens; later developments had them created with a harder-edged style influenced by American comics. The franchise gained momentum with its first anime incarnation, Digimon Adventure, and an early video game, Digimon World, both released in 1999. Several seasons of the anime and films based on them have aired, and the video game series has expanded into genres such as role-playing, racing, fighting, and MMORPGs. Other media forms have also been released.
What influenced the look of the Digimons?
Tamagotchi or nano Giga Pet toys

Poverty is a good indicator of the rate of infectious diarrhea in a population. This association does not stem from poverty itself, but rather from the conditions under which impoverished people live. The absence of certain resources compromises the ability of the poor to defend themselves against infectious diarrhea. "Poverty is associated with poor housing, crowding, dirt floors, lack of access to clean water or to sanitary disposal of fecal waste (sanitation), cohabitation with domestic animals that may carry human pathogens, and a lack of refrigerated storage for food, all of which increase the frequency of diarrhea... Poverty also restricts the ability to provide age-appropriate, nutritionally balanced diets or to modify diets when diarrhea develops so as to mitigate and repair nutrient losses. The impact is exacerbated by the lack of adequate, available, and affordable medical care."
What causes this to be exacerbated?
the lack of adequate, available, and affordable medical care.

The Mongol prince Godan, a grandson of Genghis Khan, raided as far as Lhasa. During his attack in 1240, Prince Godan summoned Sakya Pandita (1182–1251), leader of the Sakya school of Tibetan Buddhism, to his court in what is now Gansu in Western China. With Sakya Pandita's submission to Godan in 1247, Tibet was officially incorporated into the Mongol Empire during the regency of Töregene Khatun (1241–1246). Michael C. van Walt van Praag writes that Godan granted Sakya Pandita temporal authority over a still politically fragmented Tibet, stating that "this investiture had little real impact" but it was significant in that it established the unique "Priest-Patron" relationship between the Mongols and the Sakya lamas.
In what years was Töregene Khatun the regent of the Mongol Empire?
1241–1246