Question: The clearance of the pathogens, either treatment-induced or spontaneous, it can be influenced by the genetic variants carried by the individual patients. For instance, for genotype 1 hepatitis C treated with Pegylated interferon-alpha-2a or Pegylated interferon-alpha-2b (brand names Pegasys or PEG-Intron) combined with ribavirin, it has been shown that genetic polymorphisms near the human IL28B gene, encoding interferon lambda 3, are associated with significant differences in the treatment-induced clearance of the virus. This finding, originally reported in Nature, showed that genotype 1 hepatitis C patients carrying certain genetic variant alleles near the IL28B gene are more possibly to achieve sustained virological response after the treatment than others. Later report from Nature demonstrated that the same genetic variants are also associated with the natural clearance of the genotype 1 hepatitis C virus.
Is there an answer to this question: What disease has no known treatment?

Answer: unanswerable


Question: The government, consisting of the monarch and the ministers, will then usually approve the proposal and the sovereign and one of the ministers signs the proposal with the addition of an enacting clause, thereafter notifying the States General that "The King assents to the proposal." It has happened in exceptional circumstances that the government does not approve a law that has been passed in parliament. In such a case, neither the monarch nor a minister will sign the bill, notifying the States General that "The King will keep the proposal under advisement." A law that has received royal assent will be published in the State Magazine, with the original being kept in the archives of the King's Offices.
Is there an answer to this question: A law that has not received royal assent will be published where?

Answer: unanswerable


Question: Mexico has a large number of department stores based in Mexico, of which the most traditional are El Palacio de Hierro (High end and luxury goods) and Liverpool (Upper-middle income), with its middle income sister store Fabricas de Francia. Sanborns owns over 100 middle income level stores throughout the country. Grupo Carso operates Sears Mexico and two high-end Saks 5th Avenue stores. Other large chains are Coppel and Elektra, which offer items for the bargain price seeker. Wal-Mart operates Suburbia for lower income shoppers, along with stores under the brand names of Wal-Mart, Bodega Aurrera, and Superama.
Is there an answer to this question: What Mexican department store typically caters to low-end goods?

Answer: unanswerable


Question: According to historian Shaye J. D. Cohen, the status of the offspring of mixed marriages was determined patrilineally in the Bible. He brings two likely explanations for the change in Mishnaic times: first, the Mishnah may have been applying the same logic to mixed marriages as it had applied to other mixtures (Kil'ayim). Thus, a mixed marriage is forbidden as is the union of a horse and a donkey, and in both unions the offspring are judged matrilineally. Second, the Tannaim may have been influenced by Roman law, which dictated that when a parent could not contract a legal marriage, offspring would follow the mother.
Is there an answer to this question: What unions were allowed along with mixed marriages?

Answer:
unanswerable