Another objection is that it is not always possible to demonstrate falsehood definitively, especially if one is using statistical criteria to evaluate a null hypothesis. More generally it is not always clear, if evidence contradicts a hypothesis, that this is a sign of flaws in the hypothesis rather than of flaws in the evidence. However, this is a misunderstanding of what Popper's philosophy of science sets out to do. Rather than offering a set of instructions that merely need to be followed diligently to achieve science, Popper makes it clear in The Logic of Scientific Discovery that his belief is that the resolution of conflicts between hypotheses and observations can only be a matter of the collective judgment of scientists, in each individual case.

What kind of criteria frequently used in science complicates the definitiveness of some hypotheses' falsification?