Input: Article: Gram-positive bacteria possess a thick cell wall containing many layers of peptidoglycan and teichoic acids. In contrast, gram-negative bacteria have a relatively thin cell wall consisting of a few layers of peptidoglycan surrounded by a second lipid membrane containing lipopolysaccharides and lipoproteins. Lipopolysaccharides, also called endotoxins, are composed of polysaccharides and lipid A that is responsible for much of the toxicity of gram-negative bacteria. Most bacteria have the gram-negative cell wall, and only the Firmicutes and Actinobacteria have the alternative gram-positive arrangement. These two groups were previously known as the low G+C and high G+C Gram-positive bacteria, respectively. These differences in structure can produce differences in antibiotic susceptibility; for instance, vancomycin can kill only gram-positive bacteria and is ineffective against gram-negative pathogens, such as Haemophilus influenzae or Pseudomonas aeruginosa. If the bacterial cell wall is entirely removed, it is called a protoplast, whereas if it is partially removed, it is called a spheroplast. β-Lactam antibiotics, such as penicillin, inhibit the formation of peptidoglycan cross-links in the bacterial cell wall. The enzyme lysozyme, found in human tears, also digests the cell wall of bacteria and is the body's main defense against eye infections.

Now answer this question: Why gram-negative cell bacteria is more toxic than gram-positive bacteria?

Output: polysaccharides and lipid A

Input: Article: The gradual spread of Buddhism into adjacent areas meant that it came into contact with new ethnical groups. During this period Buddhism was exposed to a variety of influences, from Persian and Greek civilization, to changing trends in non-Buddhist Indian religions—themselves influenced by Buddhism. Striking examples of this syncretistic development can be seen in the emergence of Greek-speaking Buddhist monarchs in the Indo-Greek Kingdom, and in the development of the Greco-Buddhist art of Gandhāra. A Greek king, Menander, has even been immortalized in the Buddhist canon.

Now answer this question: Who was the Greek king immortalized in Buddhist canon?

Output: Menander

Input: Article: Marcin Woźniak and colleagues (2010) searched for specifically Slavic sub-group of R1a1a [M17]. Working with haplotypes, they found a pattern among Western Slavs which turned out to correspond to a newly discovered marker, M458, which defines subclade R1a1a7. This marker correlates remarkably well with the distribution of Slavic-speakers today. The team led by Peter Underhill, which discovered M458, did not consider the possibility that this was a Slavic marker, since they used the "evolutionary effective" mutation rate, which gave a date far too old to be Slavic. Woźniak and colleagues pointed out that the pedigree mutation rate, giving a later date, is more consistent with the archaeological record.

Now answer this question: When did Marcin Woźniak search specifically for Slavic sub-group of R1a1a [M17]?

Output:
2010