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Ephesus is a cultic centre of Mary, the site of the first Church dedicated to her and the rumoured place of her death. Ephesus was previously a centre for worship of Artemis a virgin goddess. The Temple of Artemis at Ephesus being regarded as one of the Seven Wonders of the Ancient World The cult of Mary was furthered by Queen Theodora in the 6th Century. According to William E. Phipps, in the book Survivals of Roman Religion "Gordon Laing argues convincingly that the worship of Artemis as both virgin and mother at the grand Ephesian temple contributed to the veneration of Mary."

Which goddess was worshipped in Ephesus before Mary?
Artemis