Problem: Antibiotics:

Several molecular mechanisms of antibacterial resistance exist. Intrinsic antibacterial resistance may be part of the genetic makeup of bacterial strains. For example, an antibiotic target may be absent from the bacterial genome. Acquired resistance results from a mutation in the bacterial chromosome or the acquisition of extra-chromosomal DNA. Antibacterial-producing bacteria have evolved resistance mechanisms that have been shown to be similar to, and may have been transferred to, antibacterial-resistant strains. The spread of antibacterial resistance often occurs through vertical transmission of mutations during growth and by genetic recombination of DNA by horizontal genetic exchange. For instance, antibacterial resistance genes can be exchanged between different bacterial strains or species via plasmids that carry these resistance genes. Plasmids that carry several different resistance genes can confer resistance to multiple antibacterials. Cross-resistance to several antibacterials may also occur when a resistance mechanism encoded by a single gene conveys resistance to more than one antibacterial compound.

What is exchanged between between bacterial strains or species via plasmids that have this resistance?
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A: antibacterial resistance genes


Problem: Eton College:

Until 18 December 2010, Eton College was an exempt charity under English law (Charities Act 1993, Schedule 2). Under the provisions of the Charities Act 2006, it is now an excepted charity, and fully registered with the Charities Commission, and is now one of the 100 largest charities in the UK. As a charity, it benefits from substantial tax breaks. It was calculated by the late David Jewell, former Master of Haileybury, that in 1992 such tax breaks saved the School about £1,945 per pupil per year, although he had no direct connection with the School. This subsidy has declined since the 2001 abolition by the Labour Government of state-funded scholarships (formerly known as "assisted places") to independent schools. However, no child attended Eton on this scheme, meaning that the actual level of state assistance to the School has always been lower. Eton's retiring Head Master, Tony Little, has claimed that the benefits that Eton provides to the local community free of charge (use of its facilities, etc.) have a higher value than the tax breaks it receives as a result of its charitable status. The fee for the academic year 2010–2011 was £29,862 (approximately US$48,600 or €35,100 as of March 2011), although the sum is considerably lower for those pupils on bursaries and scholarships.

Why is being a charity beneficial to Eton?
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A: substantial tax breaks


Problem: Pharmaceutical industry:

Early progress toward the development of vaccines occurred throughout this period, primarily in the form of academic and government-funded basic research directed toward the identification of the pathogens responsible for common communicable diseases. In 1885 Louis Pasteur and Pierre Paul Émile Roux created the first rabies vaccine. The first diphtheria vaccines were produced in 1914 from a mixture of diphtheria toxin and antitoxin (produced from the serum of an inoculated animal), but the safety of the inoculation was marginal and it was not widely used. The United States recorded 206,000 cases of diphtheria in 1921 resulting in 15,520 deaths. In 1923 parallel efforts by Gaston Ramon at the Pasteur Institute and Alexander Glenny at the Wellcome Research Laboratories (later part of GlaxoSmithKline) led to the discovery that a safer vaccine could be produced by treating diphtheria toxin with formaldehyde. In 1944, Maurice Hilleman of Squibb Pharmaceuticals developed the first vaccine against Japanese encephelitis. Hilleman would later move to Merck where he would play a key role in the development of vaccines against measles, mumps, chickenpox, rubella, hepatitis A, hepatitis B, and meningitis.

How many deaths occurred due to encephelitis?
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A: unanswerable


Problem: PlayStation 3:

Tech media website CNET gave new Super Slim 4 out of 5 stars ("Excellent"), saying "The Super Slim PlayStation 3 shrinks a powerful gaming machine into an even tinier package while maintaining the same features as its predecessors: a great gaming library and a strong array of streaming services [...]", whilst also criticising the "cheap" design and disc-loader, stating: "Sometimes [the cover] doesn't catch and you feel like you're using one of those old credit card imprinter machines. In short, it feels cheap. You don't realize how convenient autoloading disc trays are until they're gone. Whether it was to cut costs or save space, this move is ultimately a step back." The criticism also was due to price, stating the cheapest Super Slim model was still more expensive than the cheapest Slim model, and that the smaller size and bigger hard drive shouldn't be considered an upgrade when the hard drive on a Slim model is easily removed and replaced. They did praise that the hard drive of the Super Slim model is "the easiest yet. Simply sliding off the side panel reveals the drive bay, which can quickly be unscrewed." They also stated that whilst the Super Slim model is not in any way an upgrade, it could be an indicator as to what's to come. "It may not be revolutionary, but the Super Slim PS3 is the same impressive machine in a much smaller package. There doesn't seem to be any reason for existing PS3 owners to upgrade, but for the prospective PS3 buyer, the Super Slim is probably the way to go if you can deal with not having a slot-loading disc drive."

What component of the Super Slim did CNET call "the hardest yet"?
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A:
unanswerable