Much of the study of the history of science has been devoted to answering questions about what science is, how it functions, and whether it exhibits large-scale patterns and trends. The sociology of science in particular has focused on the ways in which scientists work, looking closely at the ways in which they "produce" and "construct" scientific knowledge. Since the 1960s, a common trend in science studies (the study of the sociology and history of science) has been to emphasize the "human component" of scientific knowledge, and to de-emphasize the view that scientific data are self-evident, value-free, and context-free. The field of Science and Technology Studies, an area that overlaps and often informs historical studies of science, focuses on the social context of science in both contemporary and historical periods.

What is the large question that the history of science answers?