South Raleigh is located along U.S. 401 south toward Fuquay-Varina and along US 70 into suburban Garner. This area is the least developed and least dense area of Raleigh (much of the area lies within the Swift Creek watershed district, where development regulations limit housing densities and construction). The area is bordered to the west by Cary, to the east by Garner, and to the southwest by Holly Springs. Neighborhoods in South Raleigh include Renaissance Park, Lake Wheeler, Swift Creek, Carolina Pines, Rhamkatte, Riverbrooke, and Enchanted Oaks.

Where is South Raleigh?