QUES: The body’s capability to react to antigen depends on a person's age, antigen type, maternal factors and the area where the antigen is presented. Neonates are said to be in a state of physiological immunodeficiency, because both their innate and adaptive immunological responses are greatly suppressed. Once born, a child’s immune system responds favorably to protein antigens while not as well to glycoproteins and polysaccharides. In fact, many of the infections acquired by neonates are caused by low virulence organisms like Staphylococcus and Pseudomonas. In neonates, opsonic activity and the ability to activate the complement cascade is very limited. For example, the mean level of C3 in a newborn is approximately 65% of that found in the adult. Phagocytic activity is also greatly impaired in newborns. This is due to lower opsonic activity, as well as diminished up-regulation of integrin and selectin receptors, which limit the ability of neutrophils to interact with adhesion molecules in the endothelium. Their monocytes are slow and have a reduced ATP production, which also limits the newborn's phagocytic activity. Although, the number of total lymphocytes is significantly higher than in adults, the cellular and humoral immunity is also impaired. Antigen-presenting cells in newborns have a reduced capability to activate T cells. Also, T cells of a newborn proliferate poorly and produce very small amounts of cytokines like IL-2, IL-4, IL-5, IL-12, and IFN-g which limits their capacity to activate the humoral response as well as the phagocitic activity of macrophage. B cells develop early during gestation but are not fully active.

Antigen cells in newborns are also struggle to do this?
What is the answer?
ANS: activate T cells
QUES: The Bengali Renaissance refers to a social reform movement during the nineteenth and early twentieth centuries in the Bengal region of India during the period of British rule dominated by English educated Bengali Hindus. The Bengal Renaissance can be said to have started with Raja Ram Mohan Roy (1772–1833) and ended with Rabindranath Tagore (1861–1941), although many stalwarts thereafter continued to embody particular aspects of the unique intellectual and creative output of the region. Nineteenth century Bengal was a unique blend of religious and social reformers, scholars, literary giants, journalists, patriotic orators, and scientists, all merging to form the image of a renaissance, and marked the transition from the 'medieval' to the 'modern'.

With whom was it said the the movement ended?
What is the answer?
ANS: Rabindranath Tagore
QUES: On March 27, 1964, the massive Good Friday earthquake killed 133 people and destroyed several villages and portions of large coastal communities, mainly by the resultant tsunamis and landslides. It was the second-most-powerful earthquake in the recorded history of the world, with a moment magnitude of 9.2. It was over one thousand times more powerful than the 1989 San Francisco earthquake. The time of day (5:36 pm), time of year and location of the epicenter were all cited as factors in potentially sparing thousands of lives, particularly in Anchorage.

How did the Good Friday earthquake compare to the 1998 San Francisco earthquake?
What is the answer?
ANS:
unanswerable