The hygiene hypothesis attempts to explain the increased rates of asthma worldwide as a direct and unintended result of reduced exposure, during childhood, to non-pathogenic bacteria and viruses. It has been proposed that the reduced exposure to bacteria and viruses is due, in part, to increased cleanliness and decreased family size in modern societies. Exposure to bacterial endotoxin in early childhood may prevent the development of asthma, but exposure at an older age may provoke bronchoconstriction. Evidence supporting the hygiene hypothesis includes lower rates of asthma on farms and in households with pets.
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): How does the hygene hypothesis explain the cause of bronchoconstriction?
Ah, so.. unanswerable

West of Fort Washington Avenue, 181st Street is largely residential, bordering Hudson Heights and having a few shops to serve the local residents. East of Fort Washington Avenue, the street becomes increasingly commercial, becoming dominated entirely by retail stores where the street reaches Broadway and continues as such until reaching the Harlem River. It is the area's major shopping district.
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): Which street marks the western boundary of the shopping distrit?
Ah, so.. Fort Washington Avenue

The game pad controllers were more-or-less copied directly from the Game & Watch machines, although the Famicom design team originally wanted to use arcade-style joysticks, even taking apart ones from American game consoles to see how they worked. However, it was eventually decided that children might step on joysticks left on the floor and their durability was also questioned. Katsuyah Nakawaka attached a Game & Watch D-pad to the Famicom prototype and found that it was easy to use and had no discomfort. Ultimately though, they did install a 15-pin expansion port on the front of the console so that an arcade-style joystick could be used optionally. The controllers were hard-wired to the console with no connectors for cost reasons.
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): Where were the game pad controllers copied from?
Ah, so..
Game & Watch machines