These quarks and leptons interact through four fundamental forces: gravity, electromagnetism, weak interactions, and strong interactions. The Standard Model of particle physics is currently the best explanation for all of physics, but despite decades of efforts, gravity cannot yet be accounted for at the quantum level; it is only described by classical physics (see quantum gravity and graviton). Interactions between quarks and leptons are the result of an exchange of force-carrying particles (such as photons) between quarks and leptons. The force-carrying particles are not themselves building blocks. As one consequence, mass and energy (which cannot be created or destroyed) cannot always be related to matter (which can be created out of non-matter particles such as photons, or even out of pure energy, such as kinetic energy). Force carriers are usually not considered matter: the carriers of the electric force (photons) possess energy (see Planck relation) and the carriers of the weak force (W and Z bosons) are massive, but neither are considered matter either. However, while these particles are not considered matter, they do contribute to the total mass of atoms, subatomic particles, and all systems that contain them.

Mass and energy can always be compared to what?