Article: Primary resistance occurs when a person becomes infected with a resistant strain of TB. A person with fully susceptible MTB may develop secondary (acquired) resistance during therapy because of inadequate treatment, not taking the prescribed regimen appropriately (lack of compliance), or using low-quality medication. Drug-resistant TB is a serious public health issue in many developing countries, as its treatment is longer and requires more expensive drugs. MDR-TB is defined as resistance to the two most effective first-line TB drugs: rifampicin and isoniazid. Extensively drug-resistant TB is also resistant to three or more of the six classes of second-line drugs. Totally drug-resistant TB is resistant to all currently used drugs. It was first observed in 2003 in Italy, but not widely reported until 2012, and has also been found in Iran and India. Bedaquiline is tentatively supported for use in multiple drug-resistant TB.

Question: If a person has TB that's resistant to rifampicin and isoniazid, which type of the disease do they have?
Ans: MDR-TB


Article: Kerry told Christianity Today in October 2004 "I'm a Catholic and I practice, but at the same time I have an open-mindedness to many other expressions of spirituality that come through different religions... I've spent some time reading and thinking about religion and trying to study it, and I've arrived at not so much a sense of the differences, but a sense of the similarities in so many ways." He said that he believed that the Torah, the Qur'an, and the Bible all share a fundamental story which connects with readers.

Question: What did Kerry tell Christianity Today that he is open-minded to?
Ans: many other expressions of spirituality that come through different religions


Article: Hayek's influence on the development of economics is widely acknowledged. Hayek is the second-most frequently cited economist (after Kenneth Arrow) in the Nobel lectures of the prize winners in economics, which is particularly striking since his own lecture was critical of the field of orthodox economics and neo-classical modelisation. A number of Nobel Laureates in economics, such as Vernon Smith and Herbert A. Simon, recognise Hayek as the greatest modern economist. Another Nobel winner, Paul Samuelson, believed that Hayek was worthy of his award but nevertheless claimed that "there were good historical reasons for fading memories of Hayek within the mainstream last half of the twentieth century economist fraternity. In 1931, Hayek's Prices and Production had enjoyed an ultra-short Byronic success. In retrospect hindsight tells us that its mumbo-jumbo about the period of production grossly misdiagnosed the macroeconomics of the 1927–1931 (and the 1931–2007) historical scene". Despite this comment, Samuelson spent the last 50 years of his life obsessed with the problems of capital theory identified by Hayek and Böhm-Bawerk, and Samuelson flatly judged Hayek to have been right and his own teacher, Joseph Schumpeter, to have been wrong on the central economic question of the 20th century, the feasibility of socialist economic planning in a production goods dominated economy.

Question: Which of Hayek's works does Samuelson cite as being incorrect regarding macroeconomics?
Ans: Prices and Production


Article: Since the middle of the 19th century, Masonic historians have sought the origins of the movement in a series of similar documents known as the Old Charges, dating from the Regius Poem in about 1425 to the beginning of the 18th century. Alluding to the membership of a lodge of operative masons, they relate a mythologised history of the craft, the duties of its grades, and the manner in which oaths of fidelity are to be taken on joining. The fifteenth century also sees the first evidence of ceremonial regalia.

Question: How long have historians been seeking information about the Masonic movement?
Ans:
middle of the 19th century