In 1941, Zuse followed his earlier machine up with the Z3, the world's first working electromechanical programmable, fully automatic digital computer. The Z3 was built with 2000 relays, implementing a 22 bit word length that operated at a clock frequency of about 5–10 Hz. Program code was supplied on punched film while data could be stored in 64 words of memory or supplied from the keyboard. It was quite similar to modern machines in some respects, pioneering numerous advances such as floating point numbers. Replacement of the hard-to-implement decimal system (used in Charles Babbage's earlier design) by the simpler binary system meant that Zuse's machines were easier to build and potentially more reliable, given the technologies available at that time. The Z3 was Turing complete.

When did Konrad Zuse create the Z3 computer?