Having been capital of a vast pre-Hispanic empire, and also the capital of richest viceroyalty within the Spanish Empire (ruling over a vast territory in the Americas and Spanish West Indies), and, finally, the capital of the United Mexican States, Mexico City has a rich history of artistic expression. Since the mesoamerican pre-Classical period the inhabitants of the settlements around Lake Texcoco produced many works of art and complex craftsmanship, some of which are today displayed at the world-renowned National Museum of Anthropology and the Templo Mayor museum. While many pieces of pottery and stone-engraving have survived, the great majority of the Amerindian iconography was destroyed during the Conquest of Mexico.

When did Mexico City lost most of its artifacts?