Problem: Pharmaceutical industry:

Some of these estimates also take into account the opportunity cost of investing capital many years before revenues are realized (see Time-value of money). Because of the very long time needed for discovery, development, and approval of pharmaceuticals, these costs can accumulate to nearly half the total expense. A direct consequence within the pharmaceutical industry value chain is that major pharmaceutical multinationals tend to increasingly outsource risks related to fundamental research, which somewhat reshapes the industry ecosystem with biotechnology companies playing an increasingly important role, and overall strategies being redefined accordingly. Some approved drugs, such as those based on re-formulation of an existing active ingredient (also referred to as Line-extensions) are much less expensive to develop.

What is re-formulations of active ingredients referred to?
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A: Line-extensions


Problem: Beyoncé:

Beyoncé has received numerous awards. As a solo artist she has sold over 15 million albums in the US, and over 118 million records worldwide (a further 60 million additionally with Destiny's Child), making her one of the best-selling music artists of all time. The Recording Industry Association of America (RIAA) listed Beyoncé as the top certified artist of the 2000s, with a total of 64 certifications. Her songs "Crazy in Love", "Single Ladies (Put a Ring on It)", "Halo", and "Irreplaceable" are some of the best-selling singles of all time worldwide. In 2009, The Observer named her the Artist of the Decade and Billboard named her the Top Female Artist and Top Radio Songs Artist of the Decade. In 2010, Billboard named her in their "Top 50 R&B/Hip-Hop Artists of the Past 25 Years" list at number 15. In 2012 VH1 ranked her third on their list of the "100 Greatest Women in Music". Beyoncé was the first female artist to be honored with the International Artist Award at the American Music Awards. She has also received the Legend Award at the 2008 World Music Awards and the Billboard Millennium Award at the 2011 Billboard Music Awards.

How many certifications was Beyonce awarded by the RIAA?
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A: 64


Problem: Appalachian Mountains:

Before the French and Indian War, the Appalachian Mountains laid on the indeterminate boundary between Britain's colonies along the Atlantic and French areas centered in the Mississippi basin. After the French and Indian War, the Proclamation of 1763 restricted settlement for Great Britain's thirteen original colonies in North America to east of the summit line of the mountains (except in the northern regions where the Great Lakes formed the boundary). Although the line was adjusted several times to take frontier settlements into account and was impossible to enforce as law, it was strongly resented by backcountry settlers throughout the Appalachians. The Proclamation Line can be seen as one of the grievances which led to the American Revolutionary War. Many frontier settlers held that the defeat of the French opened the land west of the mountains to English settlement, only to find settlement barred by the British King's proclamation. The backcountry settlers who fought in the Illinois campaign of George Rogers Clark were motivated to secure their settlement of Kentucky.

What was the general opinion of the law?
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A: it was strongly resented by backcountry settlers throughout the Appalachians


Problem: Light-emitting diode:

Since LED efficacy is inversely proportional to operating temperature, LED technology is well suited for supermarket freezer lighting. Because LEDs produce less waste heat than incandescent lamps, their use in freezers can save on refrigeration costs as well. However, they may be more susceptible to frost and snow buildup than incandescent lamps, so some LED lighting systems have been designed with an added heating circuit. Additionally, research has developed heat sink technologies that will transfer heat produced within the junction to appropriate areas of the light fixture.

LED efficacy is not inversely proportional to what?
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A:
unanswerable