While most Hokkien morphemes have standard designated characters, they are not always etymological or phono-semantic. Similar-sounding, similar-meaning or rare characters are commonly borrowed or substituted to represent a particular morpheme. Examples include "beautiful" (美 bí is the literary form), whose vernacular morpheme suí is represented by characters like 媠 (an obsolete character), 婎 (a vernacular reading of this character) and even 水 (transliteration of the sound suí), or "tall" (高 ko is the literary form), whose morpheme kôan is 懸. Common grammatical particles are not exempt; the negation particle m̄ (not) is variously represented by 毋, 呣 or 唔, among others. In other cases, characters are invented to represent a particular morpheme (a common example is the character 𪜶 in, which represents the personal pronoun "they"). In addition, some characters have multiple and unrelated pronunciations, adapted to represent Hokkien words. For example, the Hokkien word bah ("meat") has been reduced to the character 肉, which has etymologically unrelated colloquial and literary readings (he̍k and jio̍k, respectively). Another case is the word 'to eat,' chia̍h, which is often transcribed in Taiwanese newspapers and media as 呷 (a Mandarin transliteration, xiā, to approximate the Hokkien term), even though its recommended character in dictionaries is 食.

Most Hokkein morphemes have what type of characters?