Context and question: Beginning as a self-help program in the mid-1960s, the Cotton Research and Promotion Program (CRPP) was organized by U.S. cotton producers in response to cotton's steady decline in market share. At that time, producers voted to set up a per-bale assessment system to fund the program, with built-in safeguards to protect their investments. With the passage of the Cotton Research and Promotion Act of 1966, the program joined forces and began battling synthetic competitors and re-establishing markets for cotton. Today, the success of this program has made cotton the best-selling fiber in the U.S. and one of the best-selling fibers in the world.[citation needed]
What prompted a help program produced by cotton producers in the 1960s?
Answer: decline in market share
Context and question: There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act.  Because medical research and development of drugs to treat such diseases is financially disadvantageous, companies that do so are rewarded with tax reductions, fee waivers, and market exclusivity on that drug for a limited time (seven years), regardless of whether the drug is protected by patents.
What is subject to patients in the United States?
Answer: unanswerable
Context and question: The cottonseed which remains after the cotton is ginned is used to produce cottonseed oil, which, after refining, can be consumed by humans like any other vegetable oil. The cottonseed meal that is left generally is fed to ruminant livestock; the gossypol remaining in the meal is toxic to monogastric animals. Cottonseed hulls can be added to dairy cattle rations for roughage. During the American slavery period, cotton root bark was used in folk remedies as an abortifacient, that is, to induce a miscarriage. Gossypol was one of the many substances found in all parts of the cotton plant and it was described by the scientists as 'poisonous pigment'. It also appears to inhibit the development of sperm or even restrict the mobility of the sperm. Also, it is thought to interfere with the menstrual cycle by restricting the release of certain hormones.
As what did early scientists describe gossypol ?
Answer:
poisonous pigment