Question: Primary resistance occurs when a person becomes infected with a resistant strain of TB. A person with fully susceptible MTB may develop secondary (acquired) resistance during therapy because of inadequate treatment, not taking the prescribed regimen appropriately (lack of compliance), or using low-quality medication. Drug-resistant TB is a serious public health issue in many developing countries, as its treatment is longer and requires more expensive drugs. MDR-TB is defined as resistance to the two most effective first-line TB drugs: rifampicin and isoniazid. Extensively drug-resistant TB is also resistant to three or more of the six classes of second-line drugs. Totally drug-resistant TB is resistant to all currently used drugs. It was first observed in 2003 in Italy, but not widely reported until 2012, and has also been found in Iran and India. Bedaquiline is tentatively supported for use in multiple drug-resistant TB.
Try to answer this question if possible: What was first reported in Iran?
Answer: unanswerable
Question: Sichuan consists of two geographically very distinct parts. The eastern part of the province is mostly within the fertile Sichuan basin (which is shared by Sichuan with Chongqing Municipality). The western Sichuan consists of the numerous mountain ranges forming the easternmost part of the Qinghai-Tibet Plateau, which are known generically as Hengduan Mountains. One of these ranges, Daxue Mountains, contains the highest point of the province Gongga Shan, at 7,556 metres (24,790 ft) above sea level.
Try to answer this question if possible: What is formed by the mountains in eastern Sichuan?
Answer: unanswerable
Question: Various benefactions make it possible to give grants each year to boys who wish, for educational or cultural reasons, to work or travel abroad. These include the Busk Fund, which supports individual ventures that show particular initiative; the C.M. Wells Memorial Trust Fund, for the promotion of visits to classical lands; the Sadler Fund, which supports, amongst others, those intending to enter the Foreign Service; and the Marsden Fund, for travel in countries where the principal language is not English.
Try to answer this question if possible: Which Fund supports travel to classical lands?
Answer: the C.M. Wells Memorial Trust Fund
Question: Typically, the warmest day of the year (1971–2000) will achieve a temperature of 26.6 °C (80 °F), although in June 1976 the temperature reached 31.6 °C (89 °F), the site record. On average, 4.25 days of the year will report a maximum temperature of 25.1 °C (77 °F) or above. During the winter half of the year, the coldest night will typically fall to −4.1 °C (25 °F) although in January 1979 the temperature fell to −8.8 °C (16 °F). Typically, 18.6 nights of the year will register an air frost.
Try to answer this question if possible: In degrees Celsius, what was the coldest temperature recorded at Plymouth between 1971 and 2000?
Answer:
−8.8 °C