After Fidel Castro rose to power in Cuba in 1959, many wealthy Cubans sought refuge in Miami, further increasing the population. The city developed businesses and cultural amenities as part of the New South. In the 1980s and 1990s, South Florida weathered social problems related to drug wars, immigration from Haiti and Latin America, and the widespread destruction of Hurricane Andrew. Racial and cultural tensions were sometimes sparked, but the city developed in the latter half of the 20th century as a major international, financial, and cultural center. It is the second-largest U.S. city (after El Paso, Texas) with a Spanish-speaking majority, and the largest city with a Cuban-American plurality.

In what year did Fidel Castro take over Cuba?