Chicago Cubs
In only his third career start, Kerry Wood struck out 20 batters against Houston on May 6, 1998. This is the franchise record and tied for the Major League record for the most strikeouts in one game by one pitcher (the only other pitcher to strike out 20 batters in a nine-inning game was Roger Clemens, who achieved it twice). The game is often considered the most dominant pitching performance of all time. Interestingly, Wood's first pitch struck home plate umpire Jerry Meals in the facemask. Wood then struck out the first five batters he faced. Wood hit one batter, Craig Biggio, and allowed one hit, a scratch single by Ricky Gutiérrez off third baseman Kevin Orie's glove. The play was nearly scored an error, which would have given Wood a no-hitter.

Q: How many batters did Kerry Wood strike out against Houston?
20