Input: Article: Antibiotics are screened for any negative effects on humans or other mammals before approval for clinical use, and are usually considered safe and most are well tolerated. However, some antibiotics have been associated with a range of adverse side effects. Side-effects range from mild to very serious depending on the antibiotics used, the microbial organisms targeted, and the individual patient. Side effects may reflect the pharmacological or toxicological properties of the antibiotic or may involve hypersensitivity reactions or anaphylaxis. Safety profiles of newer drugs are often not as well established as for those that have a long history of use. Adverse effects range from fever and nausea to major allergic reactions, including photodermatitis and anaphylaxis. Common side-effects include diarrhea, resulting from disruption of the species composition in the intestinal flora, resulting, for example, in overgrowth of pathogenic bacteria, such as Clostridium difficile. Antibacterials can also affect the vaginal flora, and may lead to overgrowth of yeast species of the genus Candida in the vulvo-vaginal area. Additional side-effects can result from interaction with other drugs, such as elevated risk of tendon damage from administration of a quinolone antibiotic with a systemic corticosteroid. Some scientists have hypothesized that the indiscriminate use of antibiotics alter the host microbiota and this has been associated with chronic disease.

Now answer this question: Why are antibiotics checked before use?

Output: negative effects on humans or other mammals

Input: Article: New Haven has a history of professional sports franchises dating back to the 19th century and has been the home to professional baseball, basketball, football, hockey, and soccer teams—including the New York Giants of the National Football League from 1973 to 1974, who played at the Yale Bowl. Throughout the second half of the 20th century, New Haven consistently had minor league hockey and baseball teams, which played at the New Haven Arena (built in 1926, demolished in 1972), New Haven Coliseum (1972–2002), and Yale Field (1928–present).

Now answer this question: At what currently defunct New Haven venues did minor league hockey and baseball teams play throughout the latter half of the 20th century?

Output: New Haven Arena (built in 1926, demolished in 1972), New Haven Coliseum (1972–2002)

Input: Article: Outside of these genealogies, comics theorists and historians have seen precedents for comics in the Lascaux cave paintings in France (some of which appear to be chronological sequences of images), Egyptian hieroglyphs, Trajan's Column in Rome, the 11th-century Norman Bayeux Tapestry, the 1370 bois Protat woodcut, the 15th-century Ars moriendi and block books, Michelangelo's The Last Judgment in the Sistine Chapel, and William Hogarth's 17th-century sequential engravings, amongst others.[b]

Now answer this question: What Michelangelo work do historians consider to be a precedent for comics?

Output:
The Last Judgment in the Sistine Chapel