Von Neumann's abstract treatment permitted him also to confront the foundational issue of determinism versus non-determinism, and in the book he presented a proof that the statistical results of quantum mechanics could not possibly be averages of an underlying set of determined "hidden variables," as in classical statistical mechanics. In 1966, John S. Bell published a paper arguing that the proof contained a conceptual error and was therefore invalid. However, in 2010, Jeffrey Bub argued that Bell had misconstrued von Neumann's proof, and pointed out that the proof, though not valid for all hidden variable theories, does rule out a well-defined and important subset. Bub also suggests that von Neumann was aware of this limitation, and that von Neumann did not claim that his proof completely ruled out hidden variable theories.

Von Neumann's abstract treatment allowed him to work on what foundational issue?