The Kushan Empire expanded out of what is now Afghanistan into the northwest of the subcontinent under the leadership of their first emperor, Kujula Kadphises, about the middle of the 1st century CE. They came of an Indo-European language speaking Central Asian tribe called the Yuezhi, a branch of which was known as the Kushans. By the time of his grandson, Kanishka, they had conquered most of northern India, at least as far as Saketa and Pataliputra, in the middle Ganges Valley, and probably as far as the Bay of Bengal.
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): Who was the first ruler of the Kushan empire?
Ah, so.. Kujula Kadphises

There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act.  Because medical research and development of drugs to treat such diseases is financially disadvantageous, companies that do so are rewarded with tax reductions, fee waivers, and market exclusivity on that drug for a limited time (seven years), regardless of whether the drug is protected by patents.
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): What is given to companies who develop drugs for "orphan diseases"?
Ah, so.. tax reductions, fee waivers, and market exclusivity on that drug for a limited time (seven years), regardless of whether the drug is protected by patents

Following the fall of Wu and the turmoil of the Wu Hu uprising against the Jin dynasty (265–420), most of elite Chinese families had collaborated with the non-Chinese rulers and military conquerors in the north. Some may have lost social privilege, and took refugee in areas south to Yangtze River. Some of the Chinese refugees from north China might have resided in areas near Hangzhou. For example, the clan of Zhuge Liang (181–234), a chancellor of the state of Shu Han from Central Plain in north China during the Three Kingdoms period, gathered together at the suburb of Hangzhou, forming an exclusive, closed village Zhuge Village (Zhege Cun), consisting of villagers all with family name "Zhuge". The village has intentionally isolated itself from the surrounding communities for centuries to this day, and only recently came to be known in public. It suggests that a small number of powerful, elite Chinese refugees from the Central Plain might have taken refugee in south of the Yangtze River. However, considering the mountainous geography and relative lack of agrarian lands in Zhejiang, most of these refugees might have resided in some areas in south China beyond Zhejiang, where fertile agrarian lands and metropolitan resources were available, mainly north Jiangsu, west Fujian, Jiangxi, Hunan, Anhui,and provinces where less cohesive, organized regional governments had been in place. Metropolitan areas of Sichuan was another hub for refugees, given that the state of Shu had long been founded and ruled by political and military elites from the Central Plain and north China. Some refugees from the north China might have found residence in south China depending on their social status and military power in the north. The rump Jin state or the Southern Dynasties vied against some elite Chinese from the Central Plain and south of the Yangtze River.
If it is possible to answer this question, answer it for me (else, reply "unanswerable"): When was the Jin Dynasty?
Ah, so..
265–420