Problem: Dutch Republic:

In the Union of Utrecht of 20 January 1579, Holland and Zeeland were granted the right to accept only one religion (in practice, Calvinism). Every other province had the freedom to regulate the religious question as it wished, although the Union stated every person should be free in the choice of personal religion and that no person should be prosecuted based on religious choice. William of Orange had been a strong supporter of public and personal freedom of religion and hoped to unite Protestants and Catholics in the new union, and, for him, the Union was a defeat. In practice, Catholic services in all provinces were quickly forbidden, and the Reformed Church became the "public" or "privileged" church in the Republic.

How did William of Orange hope to unite Holland and Zeeland?
---
A: unanswerable


Problem: For vertebrates, the early stages of neural development are similar across all species. As the embryo transforms from a round blob of cells into a wormlike structure, a narrow strip of ectoderm running along the midline of the back is induced to become the neural plate, the precursor of the nervous system. The neural plate folds inward to form the neural groove, and then the lips that line the groove merge to enclose the neural tube, a hollow cord of cells with a fluid-filled ventricle at the center. At the front end, the ventricles and cord swell to form three vesicles that are the precursors of the forebrain, midbrain, and hindbrain. At the next stage, the forebrain splits into two vesicles called the telencephalon (which will contain the cerebral cortex, basal ganglia, and related structures) and the diencephalon (which will contain the thalamus and hypothalamus). At about the same time, the hindbrain splits into the metencephalon (which will contain the cerebellum and pons) and the myelencephalon (which will contain the medulla oblongata). Each of these areas contains proliferative zones where neurons and glial cells are generated; the resulting cells then migrate, sometimes for long distances, to their final positions.
The precursor of the nervous system is called what in vertebrates?
---
Answer: the neural plate


Q: What is a question about this article? If the question is unanswerable, say "unanswerable".
Until 2005, the United Nations General Assembly annually adopted a detailed resolution about the situation in Myanmar by consensus. But in 2006 a divided United Nations General Assembly voted through a resolution that strongly called upon the government of Myanmar to end its systematic violations of human rights. In January 2007, Russia and China vetoed a draft resolution before the United Nations Security Council calling on the government of Myanmar to respect human rights and begin a democratic transition. South Africa also voted against the resolution.
What occurred in the United Nations general convening in 2006 ?
A: voted through a resolution that strongly called upon the government of Myanmar to end its systematic violations of human rights.


Context and question: Greece has one of the longest histories of any country, and is considered the cradle of Western civilization, and as such, is the birthplace of democracy, Western philosophy, the Olympic Games, Western literature, historiography, political science, major scientific and mathematical principles, and Western drama, including both tragedy and comedy. Greece was first unified under Philip of Macedon in the fourth century BC. His son Alexander the Great rapidly conquered much of the ancient world, spreading Greek culture and science from the eastern Mediterranean to the Indus River. Annexed by Rome in the second century BC, Greece became an integral part of the Roman Empire and its successor, the Byzantine Empire. The first century AD saw the establishment of the Greek Orthodox Church, which shaped the modern Greek identity and transmitted Greek traditions to the wider Orthodox World. Falling under Ottoman dominion in the mid-15th century, the modern nation state of Greece emerged in 1830 following the war of independence. Greece's rich historical legacy is reflected in large part by its 17 UNESCO World Heritage Sites, among the most in Europe and the world.
Greece came part of what empire in the 2nd century BC?
Answer: Rome


Question: One of the most influential works during this burgeoning period was Niccolò Machiavelli's The Prince, written between 1511–12 and published in 1532, after Machiavelli's death. That work, as well as The Discourses, a rigorous analysis of the classical period, did much to influence modern political thought in the West. A minority (including Jean-Jacques Rousseau) interpreted The Prince as a satire meant to be given to the Medici after their recapture of Florence and their subsequent expulsion of Machiavelli from Florence. Though the work was written for the di Medici family in order to perhaps influence them to free him from exile, Machiavelli supported the Republic of Florence rather than the oligarchy of the di Medici family. At any rate, Machiavelli presents a pragmatic and somewhat consequentialist view of politics, whereby good and evil are mere means used to bring about an end—i.e., the secure and powerful state. Thomas Hobbes, well known for his theory of the social contract, goes on to expand this view at the start of the 17th century during the English Renaissance. Although neither Machiavelli nor Hobbes believed in the divine right of kings, they both believed in the inherent selfishness of the individual. It was necessarily this belief that led them to adopt a strong central power as the only means of preventing the disintegration of the social order.
Is there an answer to this question: What influential work was written in 1532?

Answer: unanswerable


Problem: Antibiotics:

Florey and Chain succeeded in purifying the first penicillin, penicillin G, in 1942, but it did not become widely available outside the Allied military before 1945. Later, Norman Heatley developed the back extraction technique for efficiently purifying penicillin in bulk. The chemical structure of penicillin was determined by Dorothy Crowfoot Hodgkin in 1945. Purified penicillin displayed potent antibacterial activity against a wide range of bacteria and had low toxicity in humans. Furthermore, its activity was not inhibited by biological constituents such as pus, unlike the synthetic sulfonamides. The discovery of such a powerful antibiotic was unprecedented, and the development of penicillin led to renewed interest in the search for antibiotic compounds with similar efficacy and safety. For their successful development of penicillin, which Fleming had accidentally discovered but could not develop himself, as a therapeutic drug, Ernst Chain and Howard Florey shared the 1945 Nobel Prize in Medicine with Fleming. Florey credited Dubos with pioneering the approach of deliberately and systematically searching for antibacterial compounds, which had led to the discovery of gramicidin and had revived Florey's research in penicillin.

When did penicillin G become available as a therapeudic drug?
---
A:
unanswerable