Question: Treatment of TB uses antibiotics to kill the bacteria. Effective TB treatment is difficult, due to the unusual structure and chemical composition of the mycobacterial cell wall, which hinders the entry of drugs and makes many antibiotics ineffective. The two antibiotics most commonly used are isoniazid and rifampicin, and treatments can be prolonged, taking several months. Latent TB treatment usually employs a single antibiotic, while active TB disease is best treated with combinations of several antibiotics to reduce the risk of the bacteria developing antibiotic resistance. People with latent infections are also treated to prevent them from progressing to active TB disease later in life. Directly observed therapy, i.e., having a health care provider watch the person take their medications, is recommended by the WHO in an effort to reduce the number of people not appropriately taking antibiotics. The evidence to support this practice over people simply taking their medications independently is poor. Methods to remind people of the importance of treatment do, however, appear effective.
Try to answer this question if possible: What part of the mycobacterial cell makes tuberculosis more difficult to treat?
Answer: wall
Question: Because it is normal to have bacterial colonization, it is difficult to know which chronic wounds are infected. Despite the huge number of wounds seen in clinical practice, there are limited quality data for evaluated symptoms and signs. A review of chronic wounds in the Journal of the American Medical Association's "Rational Clinical Examination Series" quantified the importance of increased pain as an indicator of infection. The review showed that the most useful finding is an increase in the level of pain [likelihood ratio (LR) range, 11-20] makes infection much more likely, but the absence of pain (negative likelihood ratio range, 0.64-0.88) does not rule out infection (summary LR 0.64-0.88).
Try to answer this question if possible: What is there unlimited quality data for evaluating despite the huge number of wounds seen in a clinical practice?
Answer: unanswerable
Question: However, leeches and their closest relatives have a body structure that is very uniform within the group but significantly different from that of other annelids, including other members of the Clitellata. In leeches there are no septa, the connective tissue layer of the body wall is so thick that it occupies much of the body, and the two coelomata are widely separated and run the length of the body. They function as the main blood vessels, although they are side-by-side rather than upper and lower. However, they are lined with mesothelium, like the coelomata and unlike the blood vessels of other annelids. Leeches generally use suckers at their front and rear ends to move like inchworms. The anus is on the upper surface of the pygidium.
Try to answer this question if possible: What type of annelids are very different from others?
Answer: leeches and their closest relatives
Question: With the six consistories, Paul VI continued the internationalization policies started by Pius XII in 1946 and continued by John XXIII. In his 1976 consistory, five of twenty cardinals originated from Africa, one of them a son of a tribal chief with fifty wives. Several prominent Latin Americans like Eduardo Francisco Pironio of Argentina; Luis Aponte Martinez of Puerto Rico and Eugênio de Araújo Sales and Aloisio Lorscheider from Brazil were also elevated by him. There were voices within the Church at the time saying that the European period of the Church was coming to a close, a view shared by Britain's Cardinal Basil Hume. At the same time, the members of the College of Cardinals lost some of their previous influences, after Paul VI decreed, that not only cardinals but also bishops too may participate in committees of the Roman Curia. The age limit of eighty years imposed by the Pope, a numerical increase of Cardinals by almost 100%, and a reform of the regal vestments of the "Princes of the Church" further contributed to a service-oriented perception of Cardinals under his pontificate. The increased number of Cardinals from the Third World and the papal emphasis on related issues was nevertheless welcomed by many in Western Europe.
Try to answer this question if possible: What type of clothing did Paul VI enact reform on?
Answer:
regal vestments