After the collapse of the talks and a controversial visit by Likud leader Ariel Sharon to the Temple Mount, the Second Intifada began. Some commentators contend that the uprising was pre-planned by Yasser Arafat due to the collapse of peace talks. Sharon became prime minister in a 2001 special election. During his tenure, Sharon carried out his plan to unilaterally withdraw from the Gaza Strip and also spearheaded the construction of the Israeli West Bank barrier, ending the Intifada. By this time 1,100 Israelis had been killed, mostly in suicide bombings. The Palestinian fatalities, by 30 April 2008, reached 4,745 killed by Israeli security forces, 44 killed by Israeli civilians, and 577 killed by Palestinians.

Who visited the Temple Mount?