Prior to moving its headquarters to Chicago, aerospace manufacturer Boeing (#30) was the largest company based in Seattle. Its largest division is still headquartered in nearby Renton, and the company has large aircraft manufacturing plants in Everett and Renton, so it remains the largest private employer in the Seattle metropolitan area. Former Seattle Mayor Greg Nickels announced a desire to spark a new economic boom driven by the biotechnology industry in 2006. Major redevelopment of the South Lake Union neighborhood is underway, in an effort to attract new and established biotech companies to the city, joining biotech companies Corixa (acquired by GlaxoSmithKline), Immunex (now part of Amgen), Trubion, and ZymoGenetics. Vulcan Inc., the holding company of billionaire Paul Allen, is behind most of the development projects in the region. While some see the new development as an economic boon, others have criticized Nickels and the Seattle City Council for pandering to Allen's interests at taxpayers' expense. Also in 2006, Expansion Magazine ranked Seattle among the top 10 metropolitan areas in the nation for climates favorable to business expansion. In 2005, Forbes ranked Seattle as the most expensive American city for buying a house based on the local income levels. In 2013, however, the magazine ranked Seattle No. 9 on its list of the Best Places for Business and Careers.

Before they moved to Chicago, what was the biggest company headquartered in Seattle?