Drug discovery and development is very expensive; of all compounds investigated for use in humans only a small fraction are eventually approved in most nations by government appointed medical institutions or boards, who have to approve new drugs before they can be marketed in those countries. In 2010 18 NMEs (New Molecular Entities) were approved and three biologics by the FDA, or 21 in total, which is down from 26 in 2009 and 24 in 2008. On the other hand, there were only 18 approvals in total in 2007 and 22 back in 2006. Since 2001, the Center for Drug Evaluation and Research has averaged 22.9 approvals a year. This approval comes only after heavy investment in pre-clinical development and clinical trials, as well as a commitment to ongoing safety monitoring. Drugs which fail part-way through this process often incur large costs, while generating no revenue in return. If the cost of these failed drugs is taken into account, the cost of developing a successful new drug (new chemical entity, or NCE), has been estimated at about 1.3 billion USD(not including marketing expenses). Professors Light and Lexchin reported in 2012, however, that the rate of approval for new drugs has been a relatively stable average rate of 15 to 25 for decades.
How many approvals of new drugs happen every year?
averaged 22.9 approvals

Many of the area's prominent museums are located in the historic cultural center neighborhood around Wayne State University and the College for Creative Studies. These museums include the Detroit Institute of Arts, the Detroit Historical Museum, Charles H. Wright Museum of African American History, the Detroit Science Center, as well as the main branch of the Detroit Public Library. Other cultural highlights include Motown Historical Museum, the Ford Piquette Avenue Plant museum (birthplace of the Ford Model T and the world's oldest car factory building open to the public), the Pewabic Pottery studio and school, the Tuskegee Airmen Museum, Fort Wayne, the Dossin Great Lakes Museum, the Museum of Contemporary Art Detroit (MOCAD), the Contemporary Art Institute of Detroit (CAID), and the Belle Isle Conservatory.
What is the name of the art museum in Detroit?
Detroit Institute of Arts

Nasser remains an iconic figure in the Arab world, particularly for his strides towards social justice and Arab unity, modernization policies, and anti-imperialist efforts. His presidency also encouraged and coincided with an Egyptian cultural boom, and launched large industrial projects, including the Aswan Dam and Helwan City. Nasser's detractors criticize his authoritarianism, his government's human rights violations, his populist relationship with the citizenry, and his failure to establish civil institutions, blaming his legacy for future dictatorial governance in Egypt. Historians describe Nasser as a towering political figure of the Middle East in the 20th century.
What century did Nasser rule in?
20th