Shift-work or chronic jet-lag have profound consequences on circadian and metabolic events in the body. Animals that are forced to eat during their resting period show increased body mass and altered expression of clock and metabolic genes.[medical citation needed] In humans, shift-work that favors irregular eating times is associated with altered insulin sensitivity and higher body mass. Shift-work also leads to increased metabolic risks for cardio-metabolic syndrome, hypertension, inflammation.
How does irregular eating during shift-work effect insulin?
insulin sensitivity

Internationally, Nigeria is infamous for a form of bank fraud dubbed 419, a type of advance fee fraud (named after Section 419 of the Nigerian Penal Code) along with the "Nigerian scam", a form of confidence trick practised by individuals and criminal syndicates. These scams involve a complicit Nigerian bank (the laws being set up loosely to allow it) and a scammer who claims to have money he needs to obtain from that bank. The victim is talked into exchanging bank account information on the premise that the money will be transferred to him, and then he'll get to keep a cut. In reality, money is taken out instead, and/or large fees (which seem small in comparison with the imaginary wealth he awaits) are deducted. In 2003, the Nigerian Economic and Financial Crimes Commission (or EFCC) was created, ostensibly to combat this and other forms of organised financial crime.
What organization was created to combat the 419 scams?
the Nigerian Economic and Financial Crimes Commission

Enlightenment era religious commentary was a response to the preceding century of religious conflict in Europe, especially the Thirty Years' War. Theologians of the Enlightenment wanted to reform their faith to its generally non-confrontational roots and to limit the capacity for religious controversy to spill over into politics and warfare while still maintaining a true faith in God. For moderate Christians, this meant a return to simple Scripture. John Locke abandoned the corpus of theological commentary in favor of an "unprejudiced examination" of the Word of God alone. He determined the essence of Christianity to be a belief in Christ the redeemer and recommended avoiding more detailed debate. Thomas Jefferson in the Jefferson Bible went further; he dropped any passages dealing with miracles, visitations of angels, and the resurrection of Jesus after his death. He tried to extract the practical Christian moral code of the New Testament.
Did John Locke want to foster or avoid increased detailed debate on the essence of Christianity?
avoid