Input: Article: Depending on a number of considerations, a company may apply for and be granted a patent for the drug, or the process of producing the drug, granting exclusivity rights typically for about 20 years. However, only after rigorous study and testing, which takes 10 to 15 years on average, will governmental authorities grant permission for the company to market and sell the drug. Patent protection enables the owner of the patent to recover the costs of research and development through high profit margins for the branded drug. When the patent protection for the drug expires, a generic drug is usually developed and sold by a competing company. The development and approval of generics is less expensive, allowing them to be sold at a lower price. Often the owner of the branded drug will introduce a generic version before the patent expires in order to get a head start in the generic market. Restructuring has therefore become routine, driven by the patent expiration of products launched during the industry's "golden era" in the 1990s and companies' failure to develop sufficient new blockbuster products to replace lost revenues.

Now answer this question: Governments grant permission to market drugs after how many years?

Output: 10 to 15 years on average


Article: Bacteria do not have a membrane-bound nucleus, and their genetic material is typically a single circular DNA chromosome located in the cytoplasm in an irregularly shaped body called the nucleoid. The nucleoid contains the chromosome with its associated proteins and RNA. The phylum Planctomycetes and candidate phylum Poribacteria may be exceptions to the general absence of internal membranes in bacteria, because they appear to have a double membrane around their nucleoids and contain other membrane-bound cellular structures. Like all living organisms, bacteria contain ribosomes, often grouped in chains called polyribosomes, for the production of proteins, but the structure of the bacterial ribosome is different from that of eukaryotes and Archaea. Bacterial ribosomes have a sedimentation rate of 70S (measured in Svedberg units): their subunits have rates of 30S and 50S. Some antibiotics bind specifically to 70S ribosomes and inhibit bacterial protein synthesis. Those antibiotics kill bacteria without affecting the larger 80S ribosomes of eukaryotic cells and without harming the host.

Question: What are the exceptions of non-internal membrane bacteria?
Ans: phylum Planctomycetes and candidate phylum Poribacteria


Here is a question about this article: Before the establishment of the Modern Greek state, the link between ancient and modern Greeks was emphasized by the scholars of Greek Enlightenment especially by Rigas Feraios. In his "Political Constitution", he addresses to the nation as "the people descendant of the Greeks". The modern Greek state was created in 1829, when the Greeks liberated a part of their historic homelands, Peloponnese, from the Ottoman Empire. The large Greek diaspora and merchant class were instrumental in transmitting the ideas of western romantic nationalism and philhellenism, which together with the conception of Hellenism, formulated during the last centuries of the Byzantine Empire, formed the basis of the Diafotismos and the current conception of Hellenism.
What is the answer to this question: From what era is the Rigas Feraios believed to be a part of ?
****
So... Greek Enlightenment


The problem: Answer a question about this article:
After Cassander's death in 298 BCE, however, Demetrius, who still maintained a sizable loyal army and fleet, invaded Macedon, seized the Macedonian throne (294) and conquered Thessaly and most of central Greece (293-291). He was defeated in 288 BC when Lysimachus of Thrace and Pyrrhus of Epirus invaded Macedon on two fronts, and quickly carved up the kingdom for themselves. Demetrius fled to central Greece with his mercenaries and began to build support there and in the northern Peloponnese. He once again laid siege to Athens after they turned on him, but then struck a treaty with the Athenians and Ptolemy, which allowed him to cross over to Asia minor and wage war on Lysimachus' holdings in Ionia, leaving his son Antigonus Gonatas in Greece. After initial successes, he was forced to surrender to Seleucus in 285 and later died in captivity. Lysimachus, who had seized Macedon and Thessaly for himself, was forced into war when Seleucus invaded his territories in Asia minor and was defeated and killed in 281 BCE at the Battle of Corupedium, near Sardis. Seleucus then attempted to conquer Lysimachus' European territories in Thrace and Macedon, but he was assassinated by Ptolemy Ceraunus ("the thunderbolt"), who had taken refuge at the Seleucid court and then had himself acclaimed as king of Macedon. Ptolemy was killed when Macedon was invaded by Gauls in 279, his head stuck on a spear and the country fell into anarchy. Antigonus II Gonatas invaded Thrace in the summer of 277 and defeated a large force of 18,000 Gauls. He was quickly hailed as king of Macedon and went on to rule for 35 years.
When did Demetrius seize the Macedonian throne?
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The answer: 294


Problem: Please answer a question about the following article about Alloy:
Alloying a metal is done by combining it with one or more other metals or non-metals that often enhance its properties. For example, steel is stronger than iron, its primary element. The electrical and thermal conductivity of alloys is usually lower than that of the pure metals. The physical properties, such as density, reactivity, Young's modulus of an alloy may not differ greatly from those of its elements, but engineering properties such as tensile strength and shear strength may be substantially different from those of the constituent materials. This is sometimes a result of the sizes of the atoms in the alloy, because larger atoms exert a compressive force on neighboring atoms, and smaller atoms exert a tensile force on their neighbors, helping the alloy resist deformation. Sometimes alloys may exhibit marked differences in behavior even when small amounts of one element are present. For example, impurities in semiconducting ferromagnetic alloys lead to different properties, as first predicted by White, Hogan, Suhl, Tian Abrie and Nakamura. Some alloys are made by melting and mixing two or more metals. Bronze, an alloy of copper and tin, was the first alloy discovered, during the prehistoric period now known as the bronze age; it was harder than pure copper and originally used to make tools and weapons, but was later superseded by metals and alloys with better properties. In later times bronze has been used for ornaments, bells, statues, and bearings. Brass is an alloy made from copper and zinc.
When was the bronze age?
A: prehistoric period


Question: Read this and answer the question

Bush and Kerry met for the third and final debate at Arizona State University on October 13. 51 million viewers watched the debate which was moderated by Bob Schieffer of CBS News. However, at the time of the ASU debate, there were 15.2 million viewers tuned in to watch the Major League Baseball playoffs broadcast simultaneously. After Kerry, responding to a question about gay rights, reminded the audience that Vice President Cheney's daughter was a lesbian, Cheney responded with a statement calling himself "a pretty angry father" due to Kerry using Cheney's daughter's sexual orientation for his political purposes.

Where was the final debate, between Kerry and Bush held?
Answer:
Arizona State University