The community of Casas Adobes is also on the Northwest Side, with the distinction of being Tucson's first suburb, established in the late 1940s. Casas Adobes is centered on the historic Casas Adobes Plaza (built in 1948). Casas Adobes is also home to Tohono Chul Park (a nature preserve) near the intersection of North Oracle Road and West Ina Road. The attempted assassination of Representative Gabrielle Giffords, and the murders of chief judge for the U.S. District Court for Arizona, John Roll and five other people on January 8, 2011, occurred at the La Toscana Village in Casas Adobes. The Foothills Mall is also located on the northwest side in Casas Adobes.

What is considered Tuscon's first suburb?