While West had encountered controversy a year prior when he stormed out of the American Music Awards of 2004 after losing Best New Artist, the rapper's first large-scale controversy came just days following Late Registration's release, during a benefit concert for Hurricane Katrina victims. In September 2005, NBC broadcast A Concert for Hurricane Relief, and West was a featured speaker. When West was presenting alongside actor Mike Myers, he deviated from the prepared script. Myers spoke next and continued to read the script. Once it was West's turn to speak again, he said, "George Bush doesn't care about black people." West's comment reached much of the United States, leading to mixed reactions; President Bush would later call it one of the most "disgusting moments" of his presidency. West raised further controversy in January 2006 when he posed on the cover of Rolling Stone wearing a crown of thorns.

The loss of which award caused Kanye to leave the American Music Awards?