Queen drew artistic influence from British rock acts of the 1960s and early 1970s, such as the Beatles, the Kinks, Cream, Led Zeppelin, Pink Floyd, the Who, Black Sabbath, Slade, Deep Purple, David Bowie, Genesis and Yes, in addition to American guitarist Jimi Hendrix, with Mercury also inspired by the gospel singer Aretha Franklin. May referred to the Beatles as being "our bible in the way they used the studio and they painted pictures and this wonderful instinctive use of harmonies." At their outset in the early 1970s, Queen's music has been characterised as "Led Zeppelin meets Yes" due to its combination of "acoustic/electric guitar extremes and fantasy-inspired multi-part song epics".

Which guitarist inspired Queen?