Medical facilities in Mali are very limited, and medicines are in short supply. Malaria and other arthropod-borne diseases are prevalent in Mali, as are a number of infectious diseases such as cholera and tuberculosis. Mali's population also suffers from a high rate of child malnutrition and a low rate of immunization. An estimated 1.9 percent of the adult and children population was afflicted with HIV/AIDS that year, among the lowest rates in Sub-Saharan Africa. An estimated 85–91 percent of Mali's girls and women have had female genital mutilation (2006 and 2001 data).

What are the two main prevalent infectious diseases of Mali?