Several molecular mechanisms of antibacterial resistance exist. Intrinsic antibacterial resistance may be part of the genetic makeup of bacterial strains. For example, an antibiotic target may be absent from the bacterial genome. Acquired resistance results from a mutation in the bacterial chromosome or the acquisition of extra-chromosomal DNA. Antibacterial-producing bacteria have evolved resistance mechanisms that have been shown to be similar to, and may have been transferred to, antibacterial-resistant strains. The spread of antibacterial resistance often occurs through vertical transmission of mutations during growth and by genetic recombination of DNA by horizontal genetic exchange. For instance, antibacterial resistance genes can be exchanged between different bacterial strains or species via plasmids that carry these resistance genes. Plasmids that carry several different resistance genes can confer resistance to multiple antibacterials. Cross-resistance to several antibacterials may also occur when a resistance mechanism encoded by a single gene conveys resistance to more than one antibacterial compound.
What is exchanged between between bacterial strains or species via plasmids that have this resistance?
antibacterial resistance genes

About 5% of the Nicaraguan population are indigenous. The largest indigenous group in Nicaragua is the Miskito people. Their territory extended from Cape Camarón, Honduras, to Rio Grande, Nicaragua along the Mosquito Coast. There is a native Miskito language, but large groups speak Miskito Coast Creole, Spanish, Rama and other languages. The Creole English came about through frequent contact with the British who colonized the area. Many are Christians. Traditional Miskito society was highly structured with a defined political structure. There was a king, but he did not have total power. Instead, the power was split between himself, a governor, a general, and by the 1750s, an admiral. Historical information on kings is often obscured by the fact that many of the kings were semi-mythical. Another major group is the Mayangna (or Sumu) people, counting some 10,000 people.
What percentage of the Nicaraguan population are indigenous?
About 5%

On July 16, 1945, with numerous other Manhattan Project personnel, von Neumann was an eyewitness to the first atomic bomb blast, code named Trinity, conducted as a test of the implosion method device, at the bombing range near Alamogordo Army Airfield, 35 miles (56 km) southeast of Socorro, New Mexico. Based on his observation alone, von Neumann estimated the test had resulted in a blast equivalent to 5 kilotons of TNT (21 TJ) but Enrico Fermi produced a more accurate estimate of 10 kilotons by dropping scraps of torn-up paper as the shock wave passed his location and watching how far they scattered. The actual power of the explosion had been between 20 and 22 kilotons. It was in von Neumann's 1944 papers that the expression "kilotons" appeared for the first time. After the war, Robert Oppenheimer remarked that the physicists involved in the Manhattan project had "known sin". Von Neumann's response was that "sometimes someone confesses a sin in order to take credit for it."
On what day was the first atomic blast?
July 16, 1945