This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.

[Q]: TB infection begins when the mycobacteria reach the pulmonary alveoli, where they invade and replicate within endosomes of alveolar macrophages. Macrophages identify the bacterium as foreign and attempt to eliminate it by phagocytosis. During this process, the bacterium is enveloped by the macrophage and stored temporarily in a membrane-bound vesicle called a phagosome. The phagosome then combines with a lysosome to create a phagolysosome. In the phagolysosome, the cell attempts to use reactive oxygen species and acid to kill the bacterium. However, M. tuberculosis has a thick, waxy mycolic acid capsule that protects it from these toxic substances. M. tuberculosis is able to reproduce inside the macrophage and will eventually kill the immune cell.
[A]: What specific part of the lungs marks the start of tuberculosis infection?


[Q]: In the Western Balkans, South Slavs and Germanic Gepids intermarried with Avar invaders, eventually producing a Slavicized population.[citation needed] In Central Europe, the Slavs intermixed with Germanic and Celtic, while the eastern Slavs encountered Uralic and Scandinavian peoples. Scandinavians (Varangians) and Finnic peoples were involved in the early formation of the Rus' state but were completely Slavicized after a century. Some Finno-Ugric tribes in the north were also absorbed into the expanding Rus population. At the time of the Magyar migration, the present-day Hungary was inhabited by Slavs, numbering about 200,000, and by Romano-Dacians who were either assimilated or enslaved by the Magyars. In the 11th and 12th centuries, constant incursions by nomadic Turkic tribes, such as the Kipchaks and the Pechenegs, caused a massive migration of East Slavic populations to the safer, heavily forested regions of the north. In the Middle Ages, groups of Saxon ore miners settled in medieval Bosnia, Serbia and Bulgaria where they were Slavicized.
[A]: Where did South Slavs and Germanic Gepids intermarried with Avar invaders?


[Q]: Direct democracy and federalism are hallmarks of the Swiss political system. Swiss citizens are subject to three legal jurisdictions: the commune, canton and federal levels. The 1848 federal constitution defines a system of direct democracy (sometimes called half-direct or representative direct democracy because it is aided by the more commonplace institutions of a representative democracy). The instruments of this system at the federal level, known as civic rights (Volksrechte, droits civiques), include the right to submit a constitutional initiative and a referendum, both of which may overturn parliamentary decisions.
[A]:
How many legal jurisdictions are Swiss citizens subject to?