Title: Treaty.
Question: In order to be considered a fundamental change, a change in circumstances must have been what at the time of the adoption of the treaty?

Title: Pharmaceutical industry.
Question: How much was the largest healthcare fraud case in the US settled for?

Title: Bacteria.
Question: What is the ratio of human/bacteria cells in human flora?

Title: Adult contemporary music.
Question:
Aside from the adult contemporary chart, on what other chart did Lionel Richie's "Hello" reach the top spot?