QUES: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extracts were of particular interest to surgeons as hemostatic agents and as treatment for shock, and a number of companies developed products based on adrenal extracts containing varying purities of the active substance. In 1897 John Abel of Johns Hopkins University identified the active principle as epinephrine, which he isolated in an impure state as the sulfate salt. Industrial chemist Jokichi Takamine later developed a method for obtaining epinephrine in a pure state, and licensed the technology to Parke Davis. Parke Davis marketed epinephrine under the trade name Adrenalin. Injected epinephrine proved to be especially efficacious for the acute treatment of asthma attacks, and an inhaled version was sold in the United States until 2011 (Primatene Mist). By 1929 epinephrine had been formulated into an inhaler for use in the treatment of nasal congestion.

Who identified the inactive substance?
What is the answer?
ANS: unanswerable
QUES: When Nike took over from Adidas as Arsenal's kit provider in 1994, Arsenal's away colours were again changed to two-tone blue shirts and shorts. Since the advent of the lucrative replica kit market, the away kits have been changed regularly, with Arsenal usually releasing both away and third choice kits. During this period the designs have been either all blue designs, or variations on the traditional yellow and blue, such as the metallic gold and navy strip used in the 2001–02 season, the yellow and dark grey used from 2005 to 2007, and the yellow and maroon of 2010 to 2013. As of 2009, the away kit is changed every season, and the outgoing away kit becomes the third-choice kit if a new home kit is being introduced in the same year.

What color was Arsenal's away colours when Adidas was the kit provider?
What is the answer?
ANS: unanswerable
QUES: The first Europeans to disembark and explore the region were the Portuguese navigators Diogo Cão in 1485 and Bartolomeu Dias in 1486; still the region was not claimed by the Portuguese crown. However, like most of Sub-Saharan Africa, Namibia was not extensively explored by Europeans until the 19th century, when traders and settlers arrived, principally from Germany and Sweden. In the late 19th century Dorsland trekkers crossed the area on their way from the Transvaal to Angola. Some of them settled in Namibia instead of continuing their journey.

When did Diogo Cao explore Namibia?
What is the answer?
ANS:
1485