Problem: The Times:

The Times was founded by publisher John Walter on 1 January 1785 as The Daily Universal Register, with Walter in the role of editor. Walter had lost his job by the end of 1784 after the insurance company where he was working went bankrupt because of the complaints of a Jamaican hurricane. Being unemployed, Walter decided to set a new business up. It was in that time when Henry Johnson invented the logography, a new typography that was faster and more precise (three years later, it was proved that it was not as efficient as had been said). Walter bought the logography's patent and to use it, he decided to open a printing house, where he would daily produce an advertising sheet. The first publication of the newspaper The Daily Universal Register in Great Britain was 1 January 1785. Unhappy because people always omitted the word Universal, Ellias changed the title after 940 editions on 1 January 1788 to The Times. In 1803, Walter handed ownership and editorship to his son of the same name. Walter Sr had spent sixteen months in Newgate Prison for libel printed in The Times, but his pioneering efforts to obtain Continental news, especially from France, helped build the paper's reputation among policy makers and financiers.

The Times was known as what name before it became The Times?
---
A: The Daily Universal Register


Problem: Predation:

A predator's effect on its prey species is hard to see in the short-term. However, if observed over a longer period of time, it is seen that the population of a predator will correlationally rise and fall with the population of its prey in a cycle similar to the boom and bust cycle of economics. If a predator overhunts its prey, the prey population will lower to numbers that are too scarce for the predators to find. This will cause the predator population to dip, decreasing the predation pressure on the prey population. The decrease in predators will allow the small number of prey left to slowly increase their population to somewhere around their previous abundance, which will allow the predator population to increase in response to the greater availability of resources. If a predator hunts its prey species to numbers too low to sustain the population in the short term, they can cause not only the extinction or extirpation of the prey but also the extinction of their own species, a phenomenon known as coextinction. This is a risk that wildlife conservationists encounter when introducing predators to prey that have not coevolved with the same or similar predators. This possibility depends largely on how well and how fast the prey species is able to adapt to the introduced predator. One way that this risk can be avoided is if the predator finds an alternative prey species or if an alternative prey species is introduced (something that ecologists and environmentalists try to avoid whenever possible). An alternative prey species would help to lift some of the predation pressure from the initial prey species, giving the population a chance to recover, however it does not guarantee that the initial prey species will be able to recover as the initial prey population may have been hunted to below sustainable numbers or to complete extinction.

Are predator's effects on prey easiest to see in the short-term or long-term?
---
A: longer period of time


Problem: Pharmaceutical industry:

Early progress toward the development of vaccines occurred throughout this period, primarily in the form of academic and government-funded basic research directed toward the identification of the pathogens responsible for common communicable diseases. In 1885 Louis Pasteur and Pierre Paul Émile Roux created the first rabies vaccine. The first diphtheria vaccines were produced in 1914 from a mixture of diphtheria toxin and antitoxin (produced from the serum of an inoculated animal), but the safety of the inoculation was marginal and it was not widely used. The United States recorded 206,000 cases of diphtheria in 1921 resulting in 15,520 deaths. In 1923 parallel efforts by Gaston Ramon at the Pasteur Institute and Alexander Glenny at the Wellcome Research Laboratories (later part of GlaxoSmithKline) led to the discovery that a safer vaccine could be produced by treating diphtheria toxin with formaldehyde. In 1944, Maurice Hilleman of Squibb Pharmaceuticals developed the first vaccine against Japanese encephelitis. Hilleman would later move to Merck where he would play a key role in the development of vaccines against measles, mumps, chickenpox, rubella, hepatitis A, hepatitis B, and meningitis.

The rabies vaccine was created in what year?
---
A: 1885


Problem: Protestantism:

The Scottish Reformation of 1560 decisively shaped the Church of Scotland. The Reformation in Scotland culminated ecclesiastically in the establishment of a church along Reformed lines, and politically in the triumph of English influence over that of France. John Knox is regarded as the leader of the Scottish Reformation. The Scottish Reformation Parliament of 1560 repudiated the pope's authority by the Papal Jurisdiction Act 1560, forbade the celebration of the Mass and approved a Protestant Confession of Faith. It was made possible by a revolution against French hegemony under the regime of the regent Mary of Guise, who had governed Scotland in the name of her absent daughter.

Whose regime made possible the Scottish Reformation?
---
A:
Mary of Guise