As early as 1650, settlers from the Virginia colony moved into the area of Albemarle Sound. By 1663, King Charles II of England granted a charter to start a new colony on the North American continent; it generally established North Carolina's borders. He named it Carolina in honor of his father Charles I. By 1665, a second charter was issued to attempt to resolve territorial questions. In 1710, owing to disputes over governance, the Carolina colony began to split into North Carolina and South Carolina. The latter became a crown colony in 1729.

In 1650, settlers from what colony moved in to Albemarie Sound?