Context and question: Feynman traveled to Brazil, where he gave courses at the BCPF (Brazilian Center for Physics Research) and near the end of his life schemed to visit the Russian land of Tuva, a dream that, because of Cold War bureaucratic problems, never became reality. The day after he died, a letter arrived for him from the Soviet government, giving him authorization to travel to Tuva. Later Feynman's daughter Michelle would realize this journey. Out of his enthusiastic interest in reaching Tuva came the phrase "Tuva or Bust" (also the title of a book about his efforts to get there), which was tossed about frequently amongst his circle of friends in hope that they, one day, could see it firsthand. The documentary movie, Genghis Blues, mentions some of his attempts to communicate with Tuva and chronicles the successful journey there by his friends. Responding to Hubert Humphrey's congratulation for his Nobel Prize, Feynman admitted to a long admiration for the then vice president.
What is the name of the film that discusses Feynman's attempt to escape from Tuva?
Answer: unanswerable
Context and question: Drug discovery and development is very expensive; of all compounds investigated for use in humans only a small fraction are eventually approved in most nations by government appointed medical institutions or boards, who have to approve new drugs before they can be marketed in those countries. In 2010 18 NMEs (New Molecular Entities) were approved and three biologics by the FDA, or 21 in total, which is down from 26 in 2009 and 24 in 2008. On the other hand, there were only 18 approvals in total in 2007 and 22 back in 2006. Since 2001, the Center for Drug Evaluation and Research has averaged 22.9 approvals a year. This approval comes only after heavy investment in pre-clinical development and clinical trials, as well as a commitment to ongoing safety monitoring. Drugs which fail part-way through this process often incur large costs, while generating no revenue in return. If the cost of these failed drugs is taken into account, the cost of developing a successful new drug (new chemical entity, or NCE), has been estimated at about 1.3 billion USD(not including marketing expenses). Professors Light and Lexchin reported in 2012, however, that the rate of approval for new drugs has been a relatively stable average rate of 15 to 25 for decades.
Who is responsible for approval or rejection of centers?
Answer: unanswerable
Context and question: Through Victoria's reign, the gradual establishment of a modern constitutional monarchy in Britain continued. Reforms of the voting system increased the power of the House of Commons at the expense of the House of Lords and the monarch. In 1867, Walter Bagehot wrote that the monarch only retained "the right to be consulted, the right to encourage, and the right to warn". As Victoria's monarchy became more symbolic than political, it placed a strong emphasis on morality and family values, in contrast to the sexual, financial and personal scandals that had been associated with previous members of the House of Hanover and which had discredited the monarchy. The concept of the "family monarchy", with which the burgeoning middle classes could identify, was solidified.
What idea was solidified to which the increasing middle classes in Britain could identify with?
Answer:
family monarchy