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There are special rules for certain rare diseases ("orphan diseases") in several major drug regulatory territories. For example, diseases involving fewer than 200,000 patients in the United States, or larger populations in certain circumstances are subject to the Orphan Drug Act.  Because medical research and development of drugs to treat such diseases is financially disadvantageous, companies that do so are rewarded with tax reductions, fee waivers, and market exclusivity on that drug for a limited time (seven years), regardless of whether the drug is protected by patents.

What is a term for rare diseases in some territories?
Answer: orphan diseases
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Soft rock reached its commercial peak in the mid-to-late 1970s with acts such as Toto, England Dan & John Ford Coley, Air Supply, Seals and Crofts, America and the reformed Fleetwood Mac, whose Rumours (1977) was the best-selling album of the decade. By 1977, some radio stations, like New York's WTFM and NBC-owned WYNY, had switched to an all-soft rock format. By the 1980s, tastes had changed and radio formats reflected this change, including musical artists such as Journey. Walter Sabo and his team at NBC brought in major personalities from the AM Band to the FM Band taking the format from a background to a foreground listening experience. The addition of major radio stars such as Dan Daniel, Steve O'Brien, Dick Summers, Don Bleu and Tom Parker made it possible to fully monetize the format and provide the foundation for financial success enjoyed to this day

During what period was adult contemporary its most commercially successful?
Answer: the mid-to-late 1970s
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Union Station is further served by four Amtrak lines: the Northeast Regional and the high-speed Acela Express provide service to New York, Washington, D.C. and Boston, and rank as the first and second busiest routes in the country; the New Haven–Springfield Line provides service to Hartford and Springfield, Massachusetts; and the Vermonter provides service to both Washington, D.C., and Vermont, 15 miles (24 km) from the Canadian border. Amtrak also codeshares with United Airlines for travel to any airport serviced by United Airlines, via Newark Airport (EWR) originating from or terminating at Union Station, (IATA: ZVE).

The train line that connects Connecticut, Massachusetts and Vermont together is known as what?
Answer:
New Haven–Springfield Line