Instead, he formulated the spearhead model of evolution, a version of genetic pluralism. According to this model, living organisms themselves have goals, and act according to these goals, each guided by a central control. In its most sophisticated form, this is the brain of humans, but controls also exist in much less sophisticated ways for species of lower complexity, such as the amoeba. This control organ plays a special role in evolution—it is the "spearhead of evolution". The goals bring the purpose into the world. Mutations in the genes that determine the structure of the control may then cause drastic changes in behaviour, preferences and goals, without having an impact on the organism's phenotype. Popper postulates that such purely behavioural changes are less likely to be lethal for the organism compared to drastic changes of the phenotype.
Is there an answer to this question (If it cannot be answered, say "unanswerable"): What does Popper think is more likely to be lethal to an organism than changes of phenotype?
unanswerable