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Pharmaceutical companies whose products are used in the three-drug cocktails for lethal injections are predominantly European, and they have strenuously objected to the use of their drugs for executions and taken steps to prevent their use. For example, Hospira, the sole American manufacturer of sodium thiopental, the critical anesthetic in the three-drug cocktail, announced in 2011 that it would no longer manufacture the drug for the American market, in part for ethical reasons and in part because its transfer of sodium thiopental manufacturing to Italy would subject it to the European Union's Torture Regulation, which forbids the use of any product manufactured within the Union for torture (as execution by lethal injection is considered by the Regulation). Since the drug manufacturers began taking these steps and the EU regulation ended the importation of drugs produced in Europe, the resulting shortage of execution drugs has led to or influenced decisions to impose moratoria in Arkansas, California, Kentucky, Louisiana, Mississippi, Montana, Nevada, North Carolina, and Tennessee.
Capital punishment in the United States