Here is a question about this article: On July 1, 2014, the University of Notre Dame and Under Armour reached an agreement in which Under Armour will provide uniforms, apparel,equipment, and monetary compensation to Notre Dame for 10 years. This contract, worth almost $100 million, is the most lucrative in the history of the NCAA. The university marching band plays at home games for most of the sports. The band, which began in 1846 and has a claim as the oldest university band in continuous existence in the United States, was honored by the National Music Council as a "Landmark of American Music" during the United States Bicentennial. The band regularly plays the school's fight song the Notre Dame Victory March, which was named as the most played and most famous fight song by Northern Illinois Professor William Studwell. According to College Fight Songs: An Annotated Anthology published in 1998, the "Notre Dame Victory March" ranks as the greatest fight song of all time.
What is the answer to this question: When did the Notre Dame marching band form?
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So... 1846


The problem: Answer a question about this article:
The Ming dynasty granted titles to lamas of schools such as the Karmapa Kargyu, but the latter had previously declined Mongol invitations to receive titles. When the Ming Yongle Emperor invited Je Tsongkhapa (1357–1419), founder of the Gelug school, to come to the Ming court and pay tribute, the latter declined. Wang and Nyima write that this was due to old age and physical weakness, and also because of efforts being made to build three major monasteries. Chen Qingying states that Tsongkhapa wrote a letter to decline the Emperor's invitation, and in this reply, Tsongkhapa wrote:
Who wrote the letter declining the Emperor's invitation?
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The answer: Tsongkhapa


Problem: Please answer a question about the following article about Bermuda:
Bermuda's modern black population contains more than one demographic group. Although the number of residents born in Africa is very small, it has tripled between 2000 and 2010 (this group also includes non-blacks). The majority of blacks in Bermuda can be termed "Bermudian blacks", whose ancestry dates back centuries between the 17th century and the end of slavery in 1834, Bermuda's black population was self-sustaining, with its growth resulting largely from natural expansion. This contrasts to the enslaved blacks of the plantation colonies, who were subjected to conditions so harsh as to drop their birth rate below the death rate, and slaveholders in the United States and the West Indies found it necessary to continue importing more enslaved blacks from Africa until the end of slavery (the same had been true for the Native Americans that the Africans had replaced on the New World plantations). The indigenous populations of many West Indian islands, and much of the South-East of what is now the United States that had survived the 16th- and 17th-century epidemics of European-introduced diseases then became the victims of large-scale slave raiding, with much of the region completely depopulated. When the supply of indigenous slaves ran out, the slaveholders looked to Africa). The ancestry of Bermuda's black population is distinguished from that of the British West Indian black population in two ways: firstly, the higher degree of European and Native American admixture; secondly, the source of the African ancestry.
Why were so many blacks repeatedly being imported from Africa?
A: conditions so harsh as to drop their birth rate below the death rate


Question: Read this and answer the question

The Classical era stringed instruments were the four instruments which form the string section of the orchestra: the violin, viola, cello and contrabass. Woodwinds included the basset clarinet, basset horn, clarinette d'amour, the Classical clarinet, the chalumeau, the flute, oboe and bassoon. Keyboard instruments included the clavichord and the fortepiano. While the harpsichord was still used in basso continuo accompaniment in the 1750s and 1760s, it fell out of use in the end of the century. Brass instruments included the buccin, the ophicleide (a serpent replacement which was the precursor of tuba) and the natural horn.

The violin, cello, contrabass and what other instrument form the string section of the orchestra?
Answer: viola


Problem: In 1838 with the amount of smuggled opium entering China approaching 1,400 tons a year, the Chinese imposed a death penalty for opium smuggling and sent a Special Imperial Commissioner, Lin Zexu, to curb smuggling. This resulted in the First Opium War (1839–42). After the war Hong Kong island was ceded to Britain under the Treaty of Nanking and the Chinese market opened to the opium traders of Britain and other nations. The Jardines and Apcar and Company dominated the trade, although P&O also tried to take a share. A Second Opium War fought by Britain and France against China lasted from 1856 until 1860 and led to the Treaty of Tientsin, which legalised the importation of opium. Legalisation stimulated domestic Chinese opium production and increased the importation of opium from Turkey and Persia. This increased competition for the Chinese market led to India reducing its opium output and diversifying its exports.
in 1838 about how many tone of  Opium was smuggled in to China per year?
The answer is the following: 1,400 tons


Input: Article: TB infection begins when the mycobacteria reach the pulmonary alveoli, where they invade and replicate within endosomes of alveolar macrophages. Macrophages identify the bacterium as foreign and attempt to eliminate it by phagocytosis. During this process, the bacterium is enveloped by the macrophage and stored temporarily in a membrane-bound vesicle called a phagosome. The phagosome then combines with a lysosome to create a phagolysosome. In the phagolysosome, the cell attempts to use reactive oxygen species and acid to kill the bacterium. However, M. tuberculosis has a thick, waxy mycolic acid capsule that protects it from these toxic substances. M. tuberculosis is able to reproduce inside the macrophage and will eventually kill the immune cell.

Now answer this question: What do you get when you combine a lysosome and a phagosome?

Output:
a phagolysosome