Lee has said that To Kill a Mockingbird is not an autobiography, but rather an example of how an author "should write about what he knows and write truthfully". Nevertheless, several people and events from Lee's childhood parallel those of the fictional Scout. Lee's father, Amasa Coleman Lee, was an attorney, similar to Atticus Finch, and in 1919, he defended two black men accused of murder. After they were convicted, hanged and mutilated, he never tried another criminal case. Lee's father was also the editor and publisher of the Monroeville newspaper. Although more of a proponent of racial segregation than Atticus, he gradually became more liberal in his later years. Though Scout's mother died when she was a baby, Lee was 25 when her mother, Frances Cunningham Finch, died. Lee's mother was prone to a nervous condition that rendered her mentally and emotionally absent. Lee had a brother named Edwin, who—like the fictional Jem—was four years older than his sister. As in the novel, a black housekeeper came daily to care for the Lee house and family.

Harper Lee has stated that To Kill a Mockingbird is not what genre of book?