Han dynasty
Emperor Zhang's (r. 75–88 AD) reign came to be viewed by later Eastern Han scholars as the high point of the dynastic house. Subsequent reigns were increasingly marked by eunuch intervention in court politics and their involvement in the violent power struggles of the imperial consort clans. With the aid of the eunuch Zheng Zhong (d. 107 AD), Emperor He (r. 88–105 AD) had Empress Dowager Dou (d. 97 AD) put under house arrest and her clan stripped of power. This was in revenge for Dou's purging of the clan of his natural mother—Consort Liang—and then concealing her identity from him. After Emperor He's death, his wife Empress Deng Sui (d. 121 AD) managed state affairs as the regent empress dowager during a turbulent financial crisis and widespread Qiang rebellion that lasted from 107 to 118 AD.

Q: When did Emperor He's reign end?
105 AD