Input: Article: Much of the study of the history of science has been devoted to answering questions about what science is, how it functions, and whether it exhibits large-scale patterns and trends. The sociology of science in particular has focused on the ways in which scientists work, looking closely at the ways in which they "produce" and "construct" scientific knowledge. Since the 1960s, a common trend in science studies (the study of the sociology and history of science) has been to emphasize the "human component" of scientific knowledge, and to de-emphasize the view that scientific data are self-evident, value-free, and context-free. The field of Science and Technology Studies, an area that overlaps and often informs historical studies of science, focuses on the social context of science in both contemporary and historical periods.

Now answer this question: What is the large question that the history of science answers?

Output: what science is

Input: Article: The simplest known circadian clock is that of the prokaryotic cyanobacteria. Recent research has demonstrated that the circadian clock of Synechococcus elongatus can be reconstituted in vitro with just the three proteins (KaiA, KaiB, KaiC) of their central oscillator. This clock has been shown to sustain a 22-hour rhythm over several days upon the addition of ATP. Previous explanations of the prokaryotic circadian timekeeper were dependent upon a DNA transcription/translation feedback mechanism.[citation needed]

Now answer this question: With how many proteins can the circadian clock of Synechococcus elongatus are needed to reproduce its effect?

Output: three proteins

Input: Article: By the mid-18th century, Charles Town had become a bustling trade center, the hub of the Atlantic trade for the southern colonies. Charles Towne was also the wealthiest and largest city south of Philadelphia, in part because of the lucrative slave trade. By 1770, it was the fourth-largest port in the colonies, after Boston, New York, and Philadelphia, with a population of 11,000—slightly more than half of them slaves. By 1708, the majority of the colony's population was slaves, and the future state would continue to be a majority of African descent until after the Great Migration of the early 20th century.

Now answer this question: Who made up the majority of Charles Town population in 1708?

Output:
slaves