In 1896, Patrick and Gilbert observed that during a prolonged period of sleep deprivation, sleepiness increases and decreases with a period of approximately 24 hours. In 1918, J.S. Szymanski showed that animals are capable of maintaining 24-hour activity patterns in the absence of external cues such as light and changes in temperature. In the early 20th century, circadian rhythms were noticed in the rhythmic feeding times of bees. Extensive experiments were done by Auguste Forel, Ingeborg Beling, and Oskar Wahl to see whether this rhythm was due to an endogenous clock.[citation needed] Ron Konopka and Seymour Benzer isolated the first clock mutant in Drosophila in the early 1970s and mapped the "period" gene, the first discovered genetic determinant of behavioral rhythmicity. Joseph Takahashi discovered the first mammalian circadian clock mutation (clockΔ19) using mice in 1994. However, recent studies show that deletion of clock does not lead to a behavioral phenotype (the animals still have normal circadian rhythms), which questions its importance in rhythm generation.
What gene did Konopka and Benzer map in the early 1970 s?
"period"

Originally, every electronic component had wire leads, and the PCB had holes drilled for each wire of each component. The components' leads were then passed through the holes and soldered to the PCB trace. This method of assembly is called through-hole construction. In 1949, Moe Abramson and Stanislaus F. Danko of the United States Army Signal Corps developed the Auto-Sembly process in which component leads were inserted into a copper foil interconnection pattern and dip soldered. The patent they obtained in 1956 was assigned to the U.S. Army. With the development of board lamination and etching techniques, this concept evolved into the standard printed circuit board fabrication process in use today. Soldering could be done automatically by passing the board over a ripple, or wave, of molten solder in a wave-soldering machine. However, the wires and holes are wasteful since drilling holes is expensive and the protruding wires are merely cut off.
What year was the patent for the Auto-Sembly process granted?
1956

The first attempt to establish a proper governing body and adopted the current set of Rugby rules was the Foot Ball Association of Canada, organized on March 24, 1873 followed by the Canadian Rugby Football Union (CRFU) founded June 12, 1880, which included teams from Ontario and Quebec. Later both the Ontario and Quebec Rugby Football Union (ORFU and QRFU) were formed (January 1883), and then the Interprovincial (1907) and Western Interprovincial Football Union (1936) (IRFU and WIFU). The CRFU reorganized into an umbrella organization forming the Canadian Rugby Union (CRU) in 1891. The original forerunners to the current Canadian Football League, was established in 1956 when the IRFU and WIFU formed an umbrella organization, The Canadian Football Council (CFC). And then in 1958 the CFC left The CRFU to become The CFL.
On which date was the first governing body for Canadian football formed?
March 24, 1873